Development of Multifunctional Materials Based on Poly(ether ether ketone) with Improved Biological Performances for Dental Applications
Open Access
- 23 February 2021
- Vol. 14 (4), 1047
- https://doi.org/10.3390/ma14041047
Abstract
The main target for the future of materials in dentistry aims to develop dental implants that will have optimal integration with the surrounding tissues, while preventing or avoiding bacterial infections. In this project, poly(ether ether ketone) (PEEK), known for its suitable biocompa-tibility and mechanical properties for dental applications, was loaded with 1, 3, and 5 wt.% ZnO nanoparticles to provide antibacterial properties and improve interaction with cells. Sample cha-racterization by X-ray diffraction (XRD), thermogravimetric analysis (TGA), and differential scanning calorimetry (DSC) as well as mechanical properties showed the presence of the nanoparticles and their effect in PEEK matrices, preserving their relevant properties for dental applications. Al-though, the incorporation of ZnO nanoparticles did not improve the mechanical properties and a slight decrease in the thermal stability of the materials was observed. Hemocompatibility and osteoblasts-like cell viability tests showed improved biological performances when ZnO was present, demonstrating high potential for dental implant applications.Funding Information
- Consejo Nacional de Ciencia y Tecnología (A1-S-34231)
- Natural Sciences and Engineering Research Council of Canada (Discovery grant to Diego Mantovani)
- Canadian Foundation of the Innovation (Infrastructure grant to DM, Linkage grant to Diego Mantovani)
This publication has 41 references indexed in Scilit:
- The Effect of Solvents, Acetone, Water, and Ethanol, on the Morphological and Optical Properties of ZnO Nanoparticles Prepared by MicrowaveJournal of Nanotechnology, 2012
- Zirconia Dental Implants: A Literature ReviewJournal of Oral Implantology, 2011
- Crystallization behavior of poly(ε‐caprolactone)/layered double hydroxide nanocompositesJournal of Applied Polymer Science, 2010
- Are ceramic implants a viable alternative to titanium implants? A systematic literature reviewClinical Oral Implants Research, 2009
- The influence of a compatibilizer on the thermal and dynamic mechanical properties of PEEK/carbon nanotube compositesNanotechnology, 2009
- Selective toxicity of zinc oxide nanoparticles to prokaryotic and eukaryotic systemsApplied Physics Letters, 2007
- Nanostructures in BiodiagnosticsChemical Reviews, 2005
- The Influence of Anion on the Coarsening Kinetics of ZnO NanoparticlesThe Journal of Physical Chemistry B, 2003
- Shock absorbability of various restorative materials used on implantsJournal of Oral Rehabilitation, 1999
- Desorbability of Chemisorbed Water on Metal Oxide Surfaces. I. Desorption Temperature of Chemisorbed Water on Hematite, Rutile and Zinc OxideBulletin of the Chemical Society of Japan, 1968