A Comprehensive Overview on COVID-19: Future Perspectives
Open Access
- 14 September 2021
- journal article
- review article
- Published by Frontiers Media SA in Frontiers in Cellular and Infection Microbiology
- Vol. 11, 744903
- https://doi.org/10.3389/fcimb.2021.744903
Abstract
The outbreak of COVID-19 has proven to be an unprecedented disaster for the whole world. The virus has inflicted billion of lives across the globe in all aspects- physically, psychologically, as well as socially. Compared to the previous strains of β-CoV genera- MERS and SARS, SARS-CoV-2 has significantly higher transmissibility and worst post-recovery implications. A frequent mutation in the initial SARS-CoV-2 strain has been a major cause of mortalities (approx. 3 million deaths) and uncontrolled virulence (approx. 1 billion positive cases). As far as clinical manifestations are concerned, this particular virus has exhibited deleterious impacts on systems other than the respiratory system (primary target organ), such as the brain, hematological system, liver, kidneys, endocrine system, etc. with no promising curatives to date. Lack of emergency treatments and shortage of life-saving drugs has promoted the repurposing of existing therapeutics along with the emergence of vaccines with the combined efforts of scientists and industrial experts in this short span. This review summarizes every single detail on COVID-19 and emphasizes undermining the future approaches to minimize its prevalence to the remaining lives.This publication has 148 references indexed in Scilit:
- Risk factors for mortality in patients with mucormycosis.Medical Mycology, 2012
- Pathogenesis of MucormycosisClinical Infectious Diseases, 2012
- The role of particle size in aerosolised pathogen transmission: A reviewJournal of Infection, 2011
- Viral evolutionPhysics of Life Reviews, 2006
- Novel Perspectives on Mucormycosis: Pathophysiology, Presentation, and ManagementClinical Microbiology Reviews, 2005
- Development and characterisation of neutralising monoclonal antibody to the SARS-coronavirusJournal of Virological Methods, 2004
- Human and avian influenza viruses target different cell types in cultures of human airway epitheliumProceedings of the National Academy of Sciences of the United States of America, 2004
- The Severe Acute Respiratory SyndromeThe New England Journal of Medicine, 2003
- Rhinocerebral mucormycosis: Results of aggressive surgical debridement and amphotericin BThe Laryngoscope, 1988
- MucormycosisAnnals of Internal Medicine, 1980