STING-Induced Inflammation — A Novel Therapeutic Target in ALS?
- 25 February 2021
- journal article
- editorial
- Published by Massachusetts Medical Society in The New England Journal of Medicine
- Vol. 384 (8), 765-767
- https://doi.org/10.1056/nejmcibr2031048
Abstract
The many causes of ALS are not fully known, but most patients with ALS have in common aggregates of the protein TDP-43 in affected regions of the central nervous system. This protein triggers an inflammatory pathway that may drive disease pathology.Keywords
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