COVID-19 spread quickly in Jordan in the past few months. Many changes have been observed in lungs of COVID-19 patients which required their hospitalization. So far, many studies have been conducted on the epidemiological features of COVID-19 illness; however, the evidence regarding the pathological influence on lungs is still lacking. Therefore, the main aim of the present study was to detect the possible association between lung computed tomography (CT) findings in COVID-19 and patients' age, body weight, vital sings, and medical regimen. The present cross-sectional study enrolled 230 COVID-19 patients in Prince Hamza Hospital in Jordan. Demographic data as well as major lung CT scan changes were obtained from the hospital records of the COVID-19 patients. The main observed major lung changes among the enrolled COVID-19 patients included ground glass opacification in 47(15.2%) patients and consolidation in 22(7.1%) patients. The higher percentage of patients with major lung changes (24%) was observed among patients above 60 years old, while (50%) of patients with no changes in their lung’s findings in the age group of 18-29 years old. Results obtained from the present study showed that only patients with major CT lung changes (9.7%) were prescribed more than three antibiotics. Additionally, 41.6 % patients with major lung CT scan changes had either dry (31.0%) or productive (10.6%) cough at the admission. Several predictors of lung CT scan changes have been detected in this study including age, BMI, medications, severity of symptoms, and cough at admission.