Evaluation of prescribing pattern of phosphodiesterase-5 inhibitors and assessing effectiveness of sildenafil and tadalafil in patients with erectile dysfunction
Open Access
- 15 January 2022
- journal article
- Published by IP Innovative Publication Pvt Ltd in Indian Journal of Pharmacy and Pharmacology
- Vol. 8 (4), 280-283
- https://doi.org/10.18231/j.ijpp.2021.050
Abstract
Several factors may affect identification and treatment of erectile dysfunction by health care providers, this study evaluates prescribing pattern of PDE-5 inhibitors and assess effectiveness of Sildenafil and Tadalafil in patients with erectile dysfunction.This is a descriptive and observational study, observed participants without providing any interventions, after fulfilling inclusion and exclusion criteria, patients were enrolled into study and informed written consent was obtained from all patients, data was obtained from medical records, analysed descriptively. International Index of Erectile Function (IIEF) Questionnaire is used in assessment of erectile dysfunction and treatment outcomes.In our study, 80% of patients were prescribed with phosphodiesterase inhibitors and 20% received nutritional supplements. 80 percent of drugs were prescribed under generic name, subjects treated with Sildenafil/Tadalafil were found to be associated with higher mean scores for questions of International Index of Erectile Function (IIEF). Tadalafil scored high in terms of sexual desire domain.PDE5 inhibitors represent major first-line oral therapy option for men with erectile dysfunction, shift of market from brand to generic products allows more freedom of choice, although multiple reports suggest general equivalency of four major PDE5 inhibitors, tadalafil suggested to be preferable.Keywords
This publication has 15 references indexed in Scilit:
- PDE5 inhibitors: considerations for preference and long-term adherenceInternational Journal of Clinical Practice, 2013
- Erectile dysfunctionThe Lancet, 2013
- Is Erectile Dysfunction a Reliable Proxy of General Male Health Status? The Case for the International Index of Erectile Function—Erectile Function DomainThe Journal of Sexual Medicine, 2012
- Patients’ preference in the treatment of erectile dysfunction: a critical review of the literatureInternational Journal of Impotence Research, 2010
- Anatomy, Physiology, and Pathophysiology of Erectile DysfunctionThe Journal of Sexual Medicine, 2010
- Patient preference and satisfaction in erectile dysfunction therapy: a comparison of the three phosphodiesterase-5 inhibitors sildenafil, vardenafil and tadalafilPatient Preference and Adherence, 2009
- Male Erectile Dysfunction and Health-Related Quality of LifeEuropean Urology, 2003
- Under-reporting of erectile dysfunction among men with unrelated urologic conditionsInternational Journal of Impotence Research, 2003
- Epidemiology of erectile dysfunctionInternational Journal of Impotence Research, 2003
- NIH Consensus Conference. Impotence. NIH Consensus Development Panel on ImpotenceJAMA, 1993