Synthesis of 5-arylazothiazoles, pyridines and thieno[2,3-b]pyridines derivatives containing 1,2,3-triazole moiety
Open Access
- 30 September 2012
- journal article
- Published by European Journal of Chemistry in European Journal of Chemistry
- Vol. 3 (3), 322-331
- https://doi.org/10.5155/eurjchem.3.3.322-331.629
Abstract
1-(2-(4,5-dihydro-3-(5-methyl-1-phenyl-1H-1,2,3-triazol-4-yl)-5-phenylpyrazol-1-yl)-4-subs-tituted-thiazol-5-yl)-2-phenyldiazene (4) and substituted pyridines (5-12) were synthesized via reaction of 1-(5-methyl-1-phenyl-1H-1,2,3-triazol-4-yl)-3-phenylprop-2-en-1-one with hydrazonoyl halides and active methylene compounds. Also, thieno[2,3-b]pyridines (14a-e) were prepared through reactions of 2-mercapto-6-(5-methyl-1-phenyl-1H-1,2,3-triazol-4-yl)-4-phenyl-pyridine-3-carbonitrile with halo ester and halo ketones, respectively. The newly synthesized derivetived were elucidated by elemental analysis, spectral data and alternative synthetic routes wherever possobile.Keywords
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