Study on the host-guest interactions during caffeine encapsulation into zeolite
Open Access
- 30 June 2015
- journal article
- Published by European Journal of Chemistry in European Journal of Chemistry
- Vol. 6 (2), 169-173
- https://doi.org/10.5155/eurjchem.6.2.169-173.1228
Abstract
The objective of this study was to investigate the equilibrium and kinetics behavior, sorption mechanism and host-guest interactions during caffeine (CAF) encapsulation in natural zeolite. The chemical, spectral and morphological properties of the newly obtained drug-carrier system were analyzed. Zeolite surface chemistry and morphology were characterized by determination of pH of zero charge, FT-IR and digital microscopy analyses. Equilibrium and kinetic sorption experiments and modeling were conducted to assess zeolite potential. Satisfactory extend of CAF encapsulation in the zeolite matrix (E 36.4%) was obtained. The probable host-quest interactions include Van der Waals interactions, H-bonds and chemical interactions between CAF functional groups and zeolite silanol groups, as well as parallel intraparticle diffusion of drug molecules in the mesopores of the mineral particles. The analyses of the experimental results indicated that natural zeolite could be successfully applied for encapsulating CAF.Keywords
This publication has 16 references indexed in Scilit:
- Lead uptake by new silica-carbon nanoparticlesEuropean Journal of Chemistry, 2013
- Modified Ponorogo bentonite for the removal of ampicillin from wastewaterJournal of Hazardous Materials, 2011
- Decaffeination of tea extracts by using poly(acrylamide-co-ethylene glycol dimethylacrylate) as adsorbentJournal of Food Engineering, 2010
- Adsorption of sulfur dioxide on chemically modified natural clinoptilolite. Acid modificationChemical Engineering Journal, 2009
- Sorptive removal of tetracycline from water by palygorskiteJournal of Hazardous Materials, 2009
- Montmorillonite as a drug delivery system: Intercalation and in vitro release of timolol maleateInternational Journal of Pharmaceutics, 2009
- Evaluation of papaya seeds as a novel non-conventional low-cost adsorbent for removal of methylene blueJournal of Hazardous Materials, 2009
- Synthetic zeolites as a new tool for drug deliveryJournal of Biomedical Materials Research Part A, 2007
- Adsorption of p-chlorophenol from aqueous solutions on bentonite and perlite.Journal of Hazardous Materials, 2002
- Kinetic Model for Lead(II) Sorption on to PeatAdsorption Science & Technology, 1998