The Use of Middle Latency Auditory Evoked Potentials (MLAEP) as Methodology for Evaluating Sedation Level in Propofol-Drug Induced Sleep Endoscopy (DISE) Procedure
Open Access
- 20 February 2021
- journal article
- research article
- Published by MDPI AG in International Journal of Environmental Research and Public Health
- Vol. 18 (4), 2070
- https://doi.org/10.3390/ijerph18042070
Abstract
To analyze the middle latency auditory evoked potential index (MLAEPi), compared to the standard bispectral index (BIS), as a method for evaluating the sedation level in drug-induced sleep endoscopy (DISE). In this controlled clinical study on a sample of 99 obstructive sleep apnea (OSA) or snoring patients, we compared the MLAEPi with the BIS after propofol infusion during the standard DISE technique in order to define the MLAEPi values within the observational window of the procedure. The DISE procedure was divided into eight steps, and we collected both MLAEPi and BIS data values from the same patient in every step. The MLAEPi showed a faster response than the BIS after propofol infusion during DISE. Therefore, the clinical use of the MLAEPi in evaluating the sedation level seems to be a good alternative to the current technological standards.This publication has 53 references indexed in Scilit:
- Polysomnographic evaluation of propofol-induced sleep in patients with respiratory sleep disorders and controlsThe Laryngoscope, 2013
- Rules for Scoring Respiratory Events in Sleep: Update of the 2007 AASM Manual for the Scoring of Sleep and Associated EventsSleep Medicine, 2012
- Assessment of obstruction level and selection of patients for obstructive sleep apnoea surgery: an evidence-based approachThe Journal of Laryngology & Otology, 2009
- The Experimental and Clinical Pharmacology of Propofol, an Anesthetic Agent with Neuroprotective PropertiesCNS Neuroscience & Therapeutics, 2008
- Effect site concentration during propofol TCI sedation: a comparison of sedation score with two pharmacokinetic modelsAnaesthesia, 2007
- The Contribution of Remifentanil to Middle Latency Auditory Evoked Potentials During Induction of Propofol AnesthesiaAnesthesia & Analgesia, 2006
- Obstructive Sleep Apnea as a Risk Factor for Stroke and DeathThe New England Journal of Medicine, 2005
- Practice Guidelines for Sedation and Analgesia by Non-AnesthesiologistsAnesthesiology, 2002
- Obstructive Sleep ApneaThe New England Journal of Medicine, 1996