Active neuroborreliosis or inflammation: are the diagnostic guidelines at stake?
- 17 December 2018
- journal article
- research article
- Published by Springer Science and Business Media LLC in Acta Neurologica Belgica
- Vol. 119 (2), 207-214
- https://doi.org/10.1007/s13760-018-01067-2
Abstract
Neuroborreliosis can induce a variety of neurological syndromes: e.g., cranial neuritis, plexitis, radiculitis, meningitis, cerebellitis, … We report on five cases of patients with a diagnosis of neuroborreliosis based on clinical symptoms, serologic tests and MR imaging results. However, neither of them fulfils the diagnostic criteria for definite neuroborreliosis. Are the diagnostic criteria still valid or is there a need to revise them? Is our diagnosis correct? Are these cases post-Lyme auto-immune neuronal inflammation, and not due to still active spirochetal infection? Do we need to consider immunosuppressive therapy instead of third-generation cephalosporins?Keywords
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