Teprotumumab for the Treatment of Active Thyroid Eye Disease
- 23 January 2020
- journal article
- research article
- Published by Massachusetts Medical Society in The New England Journal of Medicine
- Vol. 382 (4), 341-352
- https://doi.org/10.1056/nejmoa1910434
Abstract
Thyroid eye disease is a debilitating, disfiguring, and potentially blinding periocular condition for which no Food and Drug Administration–approved medical therapy is available. Strong evidence has implicated the insulin-like growth factor I receptor (IGF-IR) in the pathogenesis of this disease.Keywords
Funding Information
- Horizon Therapeutics plc
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