Experiment of a novel four-spherical intrauterine contraceptive device with nickel-titanium
Open Access
- 20 October 2020
- journal article
- Published by Heighten Science Publications Corporation in Clinical Journal of Obstetrics and Gynecology
- Vol. 3 (2), 142-144
- https://doi.org/10.29328/journal.cjog.1001068
Abstract
The aim of this study was to develop a novel four-spherical intrauterine contraceptive device (4-SIUD) with nickel-titanium (Ni-Ti) for human, and to evaluate the contraceptive effect. The 4-SIUD composed of 4 mesh spheres and 5 support arms. The shape of 4-SIUD was like a “T”. The height (H), upper width (D) and thickness of the 4-SIUD for macaques were 0.8 cm, 0.5 cm and 0.3 cm, and for human were 4.5 cm, 4.0 cm and 0.8 cm, respectively. The 4-SIUD was inserted into 5 macaques and pregnancy was not observed at 12 months. Three women used the 4-SIUD for 12 months, uterine perforations, expulsion, pain, and pelvic inflammatory did not occur. The results suggested that the 4-SIUD is appropriate for rhesus macaques and human use, and has a good contraceptive effect.Keywords
This publication has 11 references indexed in Scilit:
- Bleeding, cramping, and satisfaction among new copper IUD users: A prospective studyPLOS ONE, 2018
- Intrauterine Device Expulsion After Postpartum PlacementObstetrics & Gynecology, 2018
- FIGO postpartum intrauterine device initiative: Complication rates across six countriesInternational Journal of Gynecology & Obstetrics, 2018
- Levonorgestrel-releasing intra-uterine systems as female contraceptivesExpert Opinion on Pharmacotherapy, 2018
- A multicenter study assessing uterine cavity width in over 400 nulliparous women seeking IUD insertion using 2D and 3D sonographyEuropean Journal of Obstetrics & Gynecology and Reproductive Biology, 2016
- A new experimental three-dimensional, reticular intrauterine device (3-DRIUD) composed of nitinol and silicone rubberContraception, 2013
- Is previous use of hormonal contraception associated with a detrimental effect on subsequent fecundity?Human Reproduction, 2004
- Uterine perforation on intrauterine device insertion: is the incidence higher than previously reported?Contraception, 2003
- Lower hormone dosage with improved cycle controlThe European Journal of Contraception & Reproductive Health Care, 2002
- Effect of domestically-made levonorgestrel-releasing intrauterine device on the endocrine system and mensentruation in monkeysJournal of Tongji Medical University, 1996