Differences in dermoscopic findings between early and mature clear cell acanthoma
- 16 March 2020
- journal article
- research article
- Published by Wiley in The Journal of Dermatology
- Vol. 47 (6), 646-650
- https://doi.org/10.1111/1346-8138.15311
Abstract
Clear cell acanthoma (CCA) is a rare benign epidermal tumor that is difficult to diagnose by visual inspection. Conversely, its diagnosis by dermoscopy is relatively easy owing to the characteristic serpiginous arrangement of coiled vessels, sometimes described as the “string‐of‐pearls” formation. However, in few published reports, the dermoscopic diagnosis of mature CCA has been reported. Here, we report the histopathological and detailed dermoscopic findings of two CCA cases. Between these, one case was of early (~6 months) CCA exhibiting the characteristic vascular string‐of‐pearls formation, whereas the other was of a more mature (~10 years) CCA; although the latter case showed combined thick and thin white intersecting lines with large coiled vessels and/or red clods, it had the string‐of‐pearls formation. Thus, regardless of CCA maturity, the string‐of‐pearls formation was present. We propose that the combination of combined thick and thin white intersecting lines along with the vascular string‐of‐pearls formation reflecting large coiled vessels and/or red clods on dermoscopy is a diagnostic clue to mature CCA.Keywords
This publication has 14 references indexed in Scilit:
- Dermoscopic findings of irritated seborrheic keratosisJournal of the European Academy of Dermatology and Venereology, 2015
- Dermoscopic features of clear cell acanthoma: five new cases and a review of existing published casesAustralasian Journal of Dermatology, 2014
- Histopathological correlation to the dermoscopic feature of “string of pearls” in clear cell acanthomaEuropean Journal of Dermatology, 2014
- Disseminated Eruptive Clear Cell Acanthoma With Spontaneous Regression: Further Evidence of an Inflammatory Origin?The American Journal of Dermatopathology, 2011
- Multiple eruptive clear cell acanthomaJournal of Dermatological Case Reports, 2010
- How to diagnose nonpigmented skin tumors: A review of vascular structures seen with dermoscopy: Part II. Nonmelanocytic skin tumorsJournal of the American Academy of Dermatology, 2010
- Report: Clear cell acanthoma: a rare clinical diagnosis prior to biopsyInternational Journal of Dermatology, 2010
- Clear Cell Acanthoma: Clinicopathologic Analysis of 37 New CasesAmerican Journal of Clinical Pathology, 1973
- CLEAR-CELL ACANTHOMA* EXPERIENCE OF 8 YEARSBritish Journal of Dermatology, 1970