Therapeutic Targeting of Metadherin Suppresses Colorectal and Lung Cancer Progression and Metastasis
Open Access
- 25 November 2020
- journal article
- research article
- Published by American Association for Cancer Research (AACR) in Cancer Research
- Vol. 81 (4), 1014-1025
- https://doi.org/10.1158/0008-5472.can-20-1876
Abstract
This study provides new insights into the mechanism of MTDH in promoting colorectal and lung cancers, as well as genetic and pharmacologic evidence supporting the development of MTDH-targeting therapeutics.Keywords
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Funding Information
- U.S. Department of Defense (BC123187)
- American Cancer Society (RP-19-180-01-CSM)
- Susan G. Komen (PDF17332118)
- NJCCR (DFHS15PPCO21)
- Rutgers Cancer Institute of New Jersey (P30CA072720)
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