Regenerative Medicine Approaches in COVID-19 Pneumonia
- 1 January 2021
- journal article
- review article
- Published by Bentham Science Publishers Ltd. in Current Stem Cell Research & Therapy
- Vol. 16 (6), 647-655
- https://doi.org/10.2174/1574888X16999210112205826
Abstract
Regenerative medicine (RM) is an interdisciplinary field that uses different approaches to accelerate the repair and regeneration or replace damaged or diseased human cells or tissues to achieve normal tissue function. These approaches include the stimulation of the body's own repair processes, transplantation of progenitor cells, stem cells, or tissues, as well as the use of cells and exosomes as delivery-vehicles for cytokines, genes, or other therapeutic agents. COVID-19 pneumonia is a specific disease consistent with diffuse alveolar damage resulting in severe hypoxemia. Therefore, the most serious cause of death from COVID-19 is lung dysfunction. Here, we consider RM approaches to cure COVID-19 pneumonia based on what RM has so far used to treat lung diseases, injuries, or pneumonia induced by other pathogens. These approaches include stem and progenitor cell transplantation, stem cell-derived exosomes, and microRNAs therapy.This publication has 56 references indexed in Scilit:
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