The system is one in each of our most advanced biological systems at intervals the body. Immunization is additionally active or passive. The active immunization involves stimulation with Associate in Nursing matter to develop medicine defenses against a future exposure and passive immunization involves administration of preformed Associate in Nursing bodies to a personal World Health Organization is already exposed to be exposed to an matter. Immunomodulatory agents originate from every plant and animal which will increase the immune responsiveness of the body against pathogens by activating the non specific system. The system dysfunction is to blame for varied diseases like allergy, asthma, arthritis, cancer and different infectious diseases. Thus modulation of immune responses an excessive amount of needed to controlling the varied infectious diseases. The texts of ancient Indian medication literature carries with it variety of plants acknowledged to promote physical and psychological state, improve defense mechanisms of the body and enhance longevity, lesser range of aspect effects against artificial immunomodulatory agent.