Tracking the international spread of SARS-CoV-2 lineages B.1.1.7 and B.1.351/501Y-V2
Open Access
- 19 May 2021
- journal article
- Published by F1000 Research Ltd in Wellcome Open Research
Abstract
Late in 2020, two genetically-distinct clusters of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with mutations of biological concern were reported, one in the United Kingdom and one in South Africa. Using a combination of data from routine surveillance, genomic sequencing and international travel we track the international dispersal of lineages B.1.1.7 and B.1.351 (variant 501Y-V2). We account for potential biases in genomic surveillance efforts by including passenger volumes from location of where the lineage was first reported, London and South Africa respectively. Using the software tool grinch (global report investigating novel coronavirus haplotypes), we track the international spread of lineages of concern with automated daily reports, Further, we have built a custom tracking website (cov-lineages.org/global_report.html) which hosts this daily report and will continue to include novel SARS-CoV-2 lineages of concern as they are detected.Keywords
Funding Information
- European Research Council (725422)
- Medical Research Council
- Wellcome Trust (206298/Z/17/Z, grant.203783/Z/16/Z)
- Branco Weiss Fellowship – Society in Science
- Instituto de Salud Carlos III (COV0020/00140)
- South African Medical Research Council
- Fast Grants (2236)
- Department of Science and Innovation (DSI) of South Africa
- Canadian Institutes of Health Research, COVID-19 Rapid Research Funding Opportunity (02179-000)
- Wellcome Trust (206298)
- EU Grant (874850 MOOD)
- Biotechnology and Biological Sciences Research Council (BB/M010996/1)
- BlueDot
- MRC SHIP
- Oxford Martin School
- Genome Research Limited
- Deutsche Forschungsgemeinschaft (SFB900, EXC2155 RESIST)
- Wellcome Trust and Royal Society Sir Henry Dale Fellowship (204311/Z/16/Z)
- UK Research & Innovation
- Medical Research Council-São Paulo Research Foundation CADDE partnership award (MR/S0195/1,FAPESP 18/14389-0)
- National Institute of Health Research
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