The Role of the Histone Methyltransferase PfSET10 in Antigenic Variation by Malaria Parasites: a Cautionary Tale
Open Access
- 24 February 2021
- journal article
- research article
- Published by American Society for Microbiology in mSphere
- Vol. 6 (1)
- https://doi.org/10.1128/msphere.01217-20
Abstract
The identification of specific epigenetic regulatory proteins in infectious organisms has become a high-profile research topic and a focus for several drug development initiatives. However, studies that define specific roles for different epigenetic modifiers occasionally report differing results, and we similarly provide evidence regarding the histone methyltransferase PfSET10 that is in stark contrast with previously published results.Funding Information
- HHS | National Institutes of Health (AI52390, AI99327)
- Deutsche Forschungsgemeinschaft (PR905/7-1, PR905/20-1)
- DAAD | German Academic Exchange, Germany
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