Contribution of hypertension and other risk factors to survival and mortality in the Russian population
Open Access
- 21 July 2021
- journal article
- Published by Silicea - Poligraf, LLC in Cardiovascular Therapy and Prevention
- Vol. 20 (5), 3003
- https://doi.org/10.15829/1728-8800-2021-3003
Abstract
Aim. To study the contribution of hypertension (HTN) to survival and mortality in the Russian population.Material and methods. This prospective observational cohort included representative samples from 11 Russian regions (men and women aged 25-64 years, n=18251) examined in 2012-2014 as part of the Epidemiology of Cardiovascular Diseases and their Risk Factors in Regions of Russian Federation (ESSE-RF) study. The examination included a questionnaire (12 modules), anthropometric and blood pressure (BP) measurements, as well as biochemical blood tests. HTN was considered aa a systolic BP ≥140 mm Hg and/or diastolic BP ≥90 mm Hg, or when a subject receives antihypertensives. Treatment efficacy was considered as the proportion of persons (%) who achieved target BP among those taking antihypertensives. Depending on HTN status, all participants were divided into 4 groups: 1) those without HTN;2) those with HTN, taking antihypertensive agents and having systolic BP ≤140 mm H. and diastolic BP ≤90 mm Hg (effective therapy);3) those with HTN, taking medications, but not achieving target BP (ineffective therapy); 4) those with HTN, not taking antihypertensives. The life status of participants was updated every 2 years. Kaplan-Meier survival curves, as well as univariate and multivariate Cox proportional hazards models were created.Results. The presence of HTN significantly reduced survival (pConclusion. The presence of HTN significantly worsens the survival rate of men and women. Special attention of medical community should be directed to increasing the proportion of effectively treated patients with HTN.Keywords
This publication has 15 references indexed in Scilit:
- Influence of arterial hypertension, smoking, and their combination on mortality (according to the results of a 27-year cohort prospective study of the unorganized population of Tomsk)Russian Journal of Cardiology, 2019
- What factors do influence arterial hypertension control in RussiaCardiovascular Therapy and Prevention, 2018
- Cardiovascular mortality in the Russian Federation and possible mechanisms of its changesZhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2018
- Association of Blood Pressure Lowering With Mortality and Cardiovascular Disease Across Blood Pressure LevelsJAMA Internal Medicine, 2018
- Systolic Blood Pressure Reduction and Risk of Cardiovascular Disease and Mortality A Systematic Review and Network Meta-analysisJAMA Cardiology, 2017
- TWENTY YEARS TRENDS OF OBESITY AND ARTERIAL HYPERTENSION AND THEIR ASSOCIATION IN RUSSIACardiovascular Therapy and Prevention, 2017
- Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysisThe Lancet, 2015
- Cardiovascular disease, chronic kidney disease, and diabetes mortality burden of cardiometabolic risk factors from 1980 to 2010: a comparative risk assessmentThe Lancet Diabetes & Endocrinology, 2014
- Hypertension prevalence, awareness, treatment and control in national surveys from England, the USA and Canada, and correlation with stroke and ischaemic heart disease mortality: a cross-sectional studyBMJ Open, 2013
- Longitudinal trends in cardiovascular mortality and blood pressure levels, prevalence, awareness, treatment, and control of hypertension in the Czech population from 1985 to 2007/2008Journal of Hypertension, 2010