This study to determine the effect of Puzzle Play Against Social Adaptability on Mental Retardation Students in SDLB Dharma Women in Bengkulu City. This research method using a research design Pre Exsperimental Design with draft form one group pretest posttest, way of taking a sample is taken using total sampling with a sample of 12 respondents. used in this study are primary data, the data acquired, processed and analyzed using univariate and bivariate analysis using T. Test The results showed that the average number of children who have mental retardation prior to the puzzle game has a social adaptation unfavorable and the average number of children who have mental retardation after doing a puzzle game has a social adaptation enough baikdan no effect between playing puzzle to adaptability social in students with mental retardation in SDLB Dharma Women in Bengkulu City p 0.004. Keywords: Mental Retardation, Puzzle games, Social Adaptation