Fulminant myocarditis: COVID or not COVID? Reinfection or co-infection?
Open Access
- 31 October 2021
- journal article
- research article
- Published by Taylor & Francis Ltd in Future Cardiology
- Vol. 17 (8), 1307-1311
- https://doi.org/10.2217/fca-2020-0237
Abstract
We describe a unique case of fulminant myocarditis in a patient with presumed SARS-CoV-2 reinfection. Patient had initial infection 4 months backand had COVID-19 antibody at the time of presentation. Endomyocardial biopsy showed lymphocytic myocarditis, that is usually seen in viral myocarditis. The molecular diagnostic testing of the endomyocardial biopsy for cardiotropic viruses was positive for Parvovirus and negative for SARS-CoV-2. Authors highly suspect co-infection of SARS-CoV-2 and Parvovirus, that possibly triggered the immune cascade resulting in fulminant myocarditis. Patient was hemodynamically unstable with ventricular tachycardia and was supported on VA ECMO and Impella CP. There was impressive recovery of left ventricular function within 48 hours, leading to decannulation of VA ECMO in 72 h. This unique case was written by the survivor herself.This publication has 11 references indexed in Scilit:
- Genomic evidence for reinfection with SARS-CoV-2: a case studyThe Lancet Infectious Diseases, 2020
- COVID-19 Re-Infection by a Phylogenetically Distinct SARS-CoV-2 Variant, First Confirmed Event in South America.SSRN Electronic Journal, 2020
- SARS-CoV-2 in cardiac tissue of a child with COVID-19-related multisystem inflammatory syndromeThe Lancet Child & Adolescent Health, 2020
- COVID-19 fulminant myocarditis: a case reportEuropean Heart Journal - Case Reports, 2020
- Description and Proposed Management of the Acute COVID-19 Cardiovascular SyndromeCirculation, 2020
- Recognizing COVID-19–related myocarditis: The possible pathophysiology and proposed guideline for diagnosis and managementHeart Rhythm, 2020
- Myocardial localization of coronavirus in COVID‐19 cardiogenic shockEuropean Journal of Heart Failure, 2020
- Clinical Presentation and Outcome in a Contemporary Cohort of Patients With Acute MyocarditisCirculation, 2018
- Parvovirus B19 Myocarditis of Fulminant EvolutionCardiology Research, 2017