New Imaging Parameters to Predict Sudden Cardiac Death in Chagas Disease
Open Access
- 8 May 2020
- journal article
- review article
- Published by MDPI AG in Tropical Medicine and Infectious Disease
- Vol. 5 (2), 74
- https://doi.org/10.3390/tropicalmed5020074
Abstract
Chronic Chagas’ cardiomyopathy is the most severe and frequent manifestation of Chagas disease, and has a high social and economic burden. New imaging modalities, such as strain echocardiography, nuclear medicine, computed tomography and cardiac magnetic resonance imaging, may detect the presence of myocardial fibrosis, inflammation or sympathetic denervation, three conditions associated with risk of sudden death, providing additional diagnostic and/or prognostic information. Unfortunately, despite its high mortality, there is no clear recommendation for early cardioverter-defibrillator implantation in patients with Chagas heart disease in the current guidelines. Ideally, the risk of sudden cardiac death may be evaluated in earlier stages of the disease using new image methods to allow the implementation of primary preventive strategies.Keywords
This publication has 43 references indexed in Scilit:
- Myocardial Deformation Analysis in Chagas Heart Disease With the Use of Speckle Tracking EchocardiographyJournal of Cardiac Failure, 2011
- Iodine-123 Metaiodobenzylguanidine Cardiac Imaging as a Method to Detect Early Sympathetic Neuronal Dysfunction in Chagasic Patients With Normal or Borderline Electrocardiogram and Preserved Ventricular FunctionClinical Nuclear Medicine, 2011
- Sustained Ventricular Tachycardia Is Associated with Regional Myocardial Sympathetic Denervation Assessed with 123I-Metaiodobenzylguanidine in Chronic Chagas CardiomyopathyJournal of Nuclear Medicine, 2011
- I Diretriz Latino-Americana para o Diagnóstico e Tratamento da Cardiopatia ChagásicaArquivos Brasileiros de Cardiologia, 2011
- Extent of Left Ventricular Scar Predicts Outcomes in Ischemic Cardiomyopathy Patients With Significantly Reduced Systolic Function: A Delayed Hyperenhancement Cardiac Magnetic Resonance StudyJACC: Cardiovascular Imaging, 2009
- Sudden cardiac death in Chagas' heart disease in the contemporary eraInternational Journal of Cardiology, 2008
- Development and Validation of a Risk Score for Predicting Death in Chagas' Heart DiseaseThe New England Journal of Medicine, 2006
- Sudden Cardiac Death in Patients with Chagas Heart Disease and Preserved Left Ventricular FunctionJournal of Cardiovascular Electrophysiology, 2006
- M-mode and two-dimensional echocardiography in chronic Chages' heart disease. A clinical and pathologic study.Circulation, 1980