ETV4 is a theranostic target in clear cell renal cell carcinoma that promotes metastasis by activating the pro-metastatic gene FOSL1 in a PI3K-AKT dependent manner
Open Access
- 1 July 2020
- journal article
- research article
- Published by Elsevier BV in Cancer Letters
- Vol. 482, 74-89
- https://doi.org/10.1016/j.canlet.2020.04.002
Abstract
No abstract availableKeywords
Funding Information
- National Natural Science Foundation of China (81472386, 81672872, 81872384, 81972785, 81773162, 81572901)
- Science and Technology Planning Project of Guangdong Province (2014B020212017, 2014B050504004, 2015B050501005, 2014A020209024)
- Natural Science Foundation of Guangdong (2016A030311011)
- Sun Yat-sen University (84000-18843409)
This publication has 71 references indexed in Scilit:
- A systemic transcriptome analysis reveals the regulation of neural stem cell maintenance by an E2F1–miRNA feedback loopNucleic Acids Research, 2013
- Elf5 inhibits the epithelial–mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2Nature, 2012
- Novel Therapies for Metastatic Renal Cell Carcinoma: Efforts to Expand beyond the VEGF/mTOR Signaling ParadigmMolecular Cancer Therapeutics, 2012
- Oncogenic ETS proteins mimic activated RAS/MAPK signaling in prostate cellsPublished by Cold Spring Harbor Laboratory ,2011
- The physics of cancer: the role of physical interactions and mechanical forces in metastasisNature Reviews Cancer, 2011
- Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteinsNature, 2005
- Novel approaches in the therapy of metastatic renal cell carcinomaWorld Journal of Urology, 2005
- Overexpression of Ets‐1 proto‐oncogene in latent and clinical prostatic carcinomasHistopathology, 2005
- A POSTOPERATIVE PROGNOSTIC NOMOGRAM PREDICTING RECURRENCE FOR PATIENTS WITH CONVENTIONAL CLEAR CELL RENAL CELL CARCINOMAJournal of Urology, 2005
- The Hallmarks of CancerCell, 2000