Cell death leaves a new TRAIL
Open Access
- 13 October 2021
- journal article
- editorial
- Published by Rockefeller University Press in The Journal of cell biology
- Vol. 220 (11)
- https://doi.org/10.1083/jcb.202109018
Abstract
Cell death involves numerous mechanisms that can be cross-regulated through a complex signaling network. In this issue, Bozkurt et al. (2021. J. Cell Biol. https://doi.org/10.1083/jcb.202010030) identify a new connection in the network: signaling from TRAIL, a canonical inducer of apoptosis, can also induce a form of cell death called entosis, which has implications for cancer progression.Keywords
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