Disorder-specific alterations of tactile sensitivity in neurodevelopmental disorders
Open Access
- 22 January 2021
- journal article
- research article
- Published by Springer Science and Business Media LLC in Communications Biology
- Vol. 4 (1), 1-15
- https://doi.org/10.1038/s42003-020-01592-y
Abstract
Alterations of tactile processing have long been identified in autism spectrum disorders (ASD) and attention-deficit/hyperactivity disorder (ADHD). However, the extent to which these alterations are disorder-specific, rather than disorder-general, and how they relate to the core symptoms of each disorder, remains unclear. We measured and compared tactile detection, discrimination, and order judgment thresholds between a large sample of children with ASD, ADHD, ASD + ADHD combined and typically developing controls. The pattern of results suggested that while difficulties with tactile detection and order judgement were more common in children with ADHD, difficulties with tactile discrimination were more common in children with ASD. Interestingly, in our subsequent correlation analyses between tactile perception and disorder-specific clinical symptoms, tactile detection and order judgment correlated exclusively with the core symptoms of ADHD, while tactile discrimination correlated exclusively with the symptoms of ASD. When taken together, these results suggest that disorder-specific alterations of lower-level sensory processes exist and are specifically related to higher-level clinical symptoms of each disorder.Keywords
This publication has 114 references indexed in Scilit:
- Schizophrenia as a Disorder of Social CommunicationSchizophrenia Research and Treatment, 2012
- A novel device for the study of somatosensory information processingJournal of Neuroscience Methods, 2012
- Motor cortex inhibitionNeurology, 2011
- Somatosensory Information Processing in the Aging PopulationFrontiers in Aging Neuroscience, 2011
- An extended multisensory temporal binding window in autism spectrum disordersExperimental Brain Research, 2010
- Impulsiveness as a timing disturbance: neurocognitive abnormalities in attention-deficit hyperactivity disorder during temporal processes and normalization with methylphenidatePhilosophical Transactions B, 2009
- Why IQ is not a covariate in cognitive studies of neurodevelopmental disordersJournal of the International Neuropsychological Society, 2009
- Driving fast-spiking cells induces gamma rhythm and controls sensory responsesNature, 2009
- Multisensory Interplay Reveals Crossmodal Influences on ‘Sensory-Specific’ Brain Regions, Neural Responses, and JudgmentsNeuron, 2008
- Tactile Perception in Adults with Autism: a Multidimensional Psychophysical StudyJournal of Autism and Developmental Disorders, 2007