Thermodynamic Uncertainty Relation and Thermodynamic Speed Limit in Deterministic Chemical Reaction Networks

Abstract

We generalize the thermodynamic uncertainty relation (TUR) and thermodynamic speed limit (TSL) for deterministic chemical reaction networks (CRNs). The scaled diffusion coefficient derived by considering the connection between macro- and mesoscopic CRNs plays an essential role in our results. The TUR shows that the product of the entropy production rate and the ratio of the scaled diffusion coefficient to the square of the rate of concentration change is bounded below by two. The TSL states a trade-off relation between speed and thermodynamic quantities, the entropy production, and the time-averaged scaled diffusion coefficient. The results are proved under the general setting of open and nonideal CRNs.