Sperm microRNAs confer depression susceptibility to offspring
Open Access
- 12 February 2021
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science Advances
- Vol. 7 (7)
- https://doi.org/10.1126/sciadv.abd7605
Abstract
Depressive phenotypes induced by paternal stress can be transferred from one generation to the next via small RNAs in the sperm.Keywords
Funding Information
- National Natural Science Foundation of China (31871295)
- National Natural Science Foundation of China (81671107)
- National Natural Science Foundation of China (31471112)
- National Natural Science Foundation of China (31741075)
- National Natural Science Foundation of China (32022015)
- National Natural Science Foundation of China (31871295)
- National Natural Science Foundation of China (31961160724)
- Fundamental Research Funds for the Central Universities (020814380146)
- State Key Laboratory of Reproductive Medicine (SKLRM-K201801)
- Jiangsu Key Research and Development Program (BE2016737)
- Jiangsu Key Research and Development Program (BK20190008)
- National Natural Science Foundation of Jiangsu Province (BK20190008)
- National Postdoctoral Program for Innovative Talents (BX20180139)
- National Natural Science Foundation of China (32000549)
This publication has 62 references indexed in Scilit:
- A novel class of tRNA-derived small RNAs extremely enriched in mature mouse spermCell Research, 2012
- Secreted microRNAs: a new form of intercellular communicationTrends in Cell Biology, 2012
- The X-Linked Intellectual Disability Protein TSPAN7 Regulates Excitatory Synapse Development and AMPAR TraffickingNeuron, 2012
- Sperm-borne microRNA-34c is required for the first cleavage division in mouseProceedings of the National Academy of Sciences of the United States of America, 2011
- The stressed synapse: the impact of stress and glucocorticoids on glutamate transmissionNature Reviews Neuroscience, 2011
- Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNACell Research, 2011
- Secreted Monocytic miR-150 Enhances Targeted Endothelial Cell MigrationMolecular Cell, 2010
- Stevia and Saccharin Preferences in Rats and MiceChemical Senses, 2010
- The molecular neurobiology of depressionNature, 2008
- Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseasesCell Research, 2008