The impact of access to water supply and sanitation on the prevalence of active trachoma in Ethiopia: A systematic review and meta-analysis
Open Access
- 9 September 2021
- journal article
- review article
- Published by Public Library of Science (PLoS) in PLoS Neglected Tropical Diseases
- Vol. 15 (9), e0009644
- https://doi.org/10.1371/journal.pntd.0009644
Abstract
Background Trachoma is a worldwide infectious disease causing blindness. Trachoma continued as a public health problem in Ethiopia due to a lack of sanitation and inadequate prevention strategies. This study aimed to identify the impact of water supply and sanitation intervention on preventing active trachoma among children. Methods Systematic literature searches were performed from 4 international databases. The search involved articles published from January 1995 up to March 2019. The Cochran Q and I2 statistical tests were used to check heterogeneity among the studies. A random-effect meta-analysis was employed to determine the pooled estimates with a 95% confidence interval (CI). Data analysis was performed using the CMA V.3 and RevMan 5 software program, and the result of the systematic review was reported using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Findings Out of 211 studies screened for the analysis, only 29 studies were finally included in this systematic review and meta-analysis. The result revealed factors that are significantly associated with increased odds of active trachoma. Accordingly, households with no access to toilet facilities (odds ratio [OR]: 2.04, 95% CI: 1.75–2.38), no access to improved water (OR: 1.58, 95% CI: 1.27–1.96), and do not practice regular face washing for children (OR: 4.19, 95% CI: 3.02–5.81) have shown increased odds of active trachoma. Besides, the results show a higher prevalence of active trachoma among children who did not wash their faces with soap and frequently. Conclusions The study found strong evidence that lack of access to water, sanitation, and hygiene (WASH) was associated with increased prevalence of active trachoma among children. Therefore, a comprehensive and partnership-oriented program is needed to tackle the problem, but further study will be required to strengthen its implementation.Keywords
This publication has 45 references indexed in Scilit:
- Integration of Water, Sanitation, and Hygiene for the Prevention and Control of Neglected Tropical Diseases: A Rationale for Inter-Sectoral CollaborationPLoS Neglected Tropical Diseases, 2013
- The Added Value of Water, Sanitation, and Hygiene Interventions to Mass Drug Administration for Reducing the Prevalence of Trachoma: A Systematic Review ExaminingJournal of Environmental and Public Health, 2013
- Association between water related factors and active trachoma in Hai district, Northern TanzaniaInfectious Diseases of Poverty, 2012
- Meta-analyses and Forest plots using a microsoft excel spreadsheet: step-by-step guide focusing on descriptive data analysisBMC Research Notes, 2012
- National Survey on Blindness, Low Vision and Trachoma in Ethiopia: Methods and Study Clusters ProfileEthiopian Journal of Health Development, 2008
- Prevalence and risk factors for trachoma and ocular Chlamydia trachomatis infection in NigerBritish Journal of Ophthalmology, 2006
- Distance to water source and altitude in relation to active trachoma in Rombo district, TanzaniaTropical Medicine & International Health, 2006
- Fixed- and random-effects models in meta-analysis.Psychological Methods, 1998
- Trachoma and water use; a case control study in a Gambian villageTransactions of the Royal Society of Tropical Medicine and Hygiene, 1991