Blood transfusion rates in Baby NINJA (Nephrotoxic Injury Negated by Just-in-Time Action)—a single-center experience
- 22 January 2021
- journal article
- research article
- Published by Springer Science and Business Media LLC in Pediatric Nephrology
- Vol. 36 (7), 1901-1905
- https://doi.org/10.1007/s00467-020-04917-5
Abstract
Background Previous studies in non-critically ill hospitalized pediatric patients have shown that daily serum creatinine monitoring for the development of nephrotoxic medication–associated acute kidney injury decreases both the rate of high nephrotoxic medication exposure and associated acute kidney injury. Attempts to spread this successful screening program have been met with concerns that daily serum creatinine monitoring in critically ill neonates with high-risk nephrotoxic medication exposure would lead to iatrogenic anemia and an increase in blood transfusion requirements. Methods We measured blood transfusion rates while implementing a system of daily serum creatinine monitoring in critically ill neonates at risk for high nephrotoxic medication–associated acute kidney injury. Results There was no correlation between blood transfusion rates and serum creatinine monitoring rates. Conclusions We recommend that critically ill neonates identified as having high-risk nephrotoxic medication exposure undergo daily screening for the development of nephrotoxic medication–associated acute kidney injury.Keywords
This publication has 18 references indexed in Scilit:
- Nephrotoxic medication exposure in very low birth weight infantsThe Journal of Maternal-Fetal & Neonatal Medicine, 2013
- Electronic Health Record Identification of Nephrotoxin Exposure and Associated Acute Kidney InjuryPEDIATRICS, 2013
- Impact of Providing Fee Data on Laboratory Test OrderingJAMA Internal Medicine, 2013
- Choosing WiselyJAMA, 2012
- Serum creatinine as stratified in the RIFLE score for acute kidney injury is associated with mortality and length of stay for children in the pediatric intensive care unitCritical Care Medicine, 2010
- Acute kidney injury is independently associated with mortality in very low birthweight infants: a matched case–control analysisPediatric Nephrology, 2009
- Acute kidney injury in critically ill newborns: What do we know? What do we need to learn?Pediatric Nephrology, 2009
- 3–5 year longitudinal follow-up of pediatric patients after acute renal failureKidney International, 2006
- Reduction in Red Blood Cell Transfusions Among Preterm Infants: Results of a Randomized Trial With an In-Line Blood Gas and Chemistry MonitorPEDIATRICS, 2005
- Statistical process control as a tool for research and healthcare improvementQuality and Safety in Health Care, 2003