Scoring of Growth of Unruptured Intracranial Aneurysms
Open Access
- 17 October 2020
- journal article
- research article
- Published by MDPI AG in Journal of Clinical Medicine
- Vol. 9 (10), 3339
- https://doi.org/10.3390/jcm9103339
Abstract
The purpose was to obtain a reliable scoring for growth of unruptured intracranial aneurysms (UIAs) in a long-term follow-up study from variables known at baseline and to compare it with the ELAPSS (Earlier subarachnoid hemorrhage, Location of the aneurysm, Age > 60 years, Population, Size of the aneurysm, and Shape of the aneurysm) score obtained from an individual-based meta-analysis. The series consists of 87 patients with 111 UIAs and 1669 person-years of follow-up between aneurysm size measurements (median follow-up time per patient 21.7, range 1.2 to 51.0 years). These were initially diagnosed between 1956 and 1978, when UIAs were not treated in our country. ELAPSS scores at baseline did not differ between those with and those without aneurysm growth. The area under the curve (AUC) for the receiver operating curve (ROC) of the ELAPSS score for predicting long-term growth was fail (0.474, 95% CI 0.345–0.603), and the optimal cut-off point was obtained at ≥7 vs. p < 0.05). The optimal cut-off point was obtained at ≥4 vs. <4 points for sensitivity (0.971) and specificity (0.304). A new simple scoring consisting of only female sex, cigarette smoking and age <40 years predicted growth of an intracranial aneurysm in long-term follow-up, significantly better than the ELAPSS score.This publication has 27 references indexed in Scilit:
- Worldwide Incidence of Aneurysmal Subarachnoid Hemorrhage According to Region, Time Period, Blood Pressure, and Smoking Prevalence in the PopulationJAMA Neurology, 2019
- Incidence of subarachnoid hemorrhage is decreasing together with decreasing smoking ratesNeurology, 2016
- The unruptured intracranial aneurysm treatment scoreNeurology, 2015
- Lifelong Rupture Risk of Intracranial Aneurysms Depends on Risk FactorsStroke, 2014
- Multidisciplinary Consensus on Assessment of Unruptured Intracranial AneurysmsStroke, 2014
- Natural History of Unruptured Intracranial AneurysmsStroke, 2013
- European Stroke Organization Guidelines for the Management of Intracranial Aneurysms and Subarachnoid HaemorrhageCerebrovascular Diseases, 2013
- Cause-specific mortality of 1-year survivors of subarachnoid hemorrhageNeurology, 2013
- Changes in case fatality of aneurysmal subarachnoid haemorrhage over time, according to age, sex, and region: a meta-analysisThe Lancet Neurology, 2009
- Prehemorrhage Risk Factors for Fatal Intracranial Aneurysm RuptureStroke, 2003