Speaking the language of lipids: the cross-talk between plants and pathogens in defence and disease
- 27 February 2021
- journal article
- review article
- Published by Springer Science and Business Media LLC in Cellular and Molecular Life Sciences
- Vol. 78 (9), 4399-4415
- https://doi.org/10.1007/s00018-021-03791-0
Abstract
Lipids and fatty acids play crucial roles in plant immunity, which have been highlighted over the past few decades. An increasing number of studies have shown that these molecules are pivotal in the interactions between plants and their diverse pathogens. The roles played by plant lipids fit in a wide spectrum ranging from the first physical barrier encountered by the pathogens, the cuticle, to the signalling pathways that trigger different immune responses and expression of defence-related genes, mediated by several lipid molecules. Moreover, lipids have been arising as candidate biomarkers of resistance or susceptibility to different pathogens. Studies on the apoplast and extracellular vesicles have been highlighting the possible role of lipids in the intercellular communication and the establishment of systemic acquired resistance during plant–pathogen interactions. From the pathogen perspective, lipid metabolism and specific lipid molecules play pivotal roles in the pathogen’s life cycle completion, being crucial during recognition by the plant and evasion from the host immune system, therefore potentiating infection. Studies conducted in the last years have contributed to a better understanding of the language of lipids during the cross-talk between plants and pathogens. However, it is essential to continue exploring the knowledge brought up to light by transcriptomics and proteomics studies towards the elucidation of lipid signalling processes during defence and disease. In this review, we present an updated overview on lipids associated to plant–pathogen interactions, exploiting their roles from the two sides of this battle.Keywords
Funding Information
- Fundação para a Ciência e a Tecnologia (PD/BD/131030/2017, UIDB/04046/2020, UIDP/04046/2020, PTDC/BIA-BQM/28539/2017, IF/00819/2015)
This publication has 176 references indexed in Scilit:
- Structural and Functional Studies of a Phosphatidic Acid-Binding Antifungal Plant Defensin MtDef4: Identification of an RGFRRR Motif Governing Fungal Cell EntryPLOS ONE, 2013
- Large-scale proteomic analysis of the grapevine leaf apoplastic fluid reveals mainly stress-related proteins and cell wall modifying enzymesBMC Plant Biology, 2013
- Repertoire, unified nomenclature and evolution of the Type III effector gene set in the Ralstonia solanacearum species complexBMC Genomics, 2013
- Plant targets for Pseudomonas syringae type III effectors: virulence targets or guarded decoys?Current Opinion in Microbiology, 2011
- The glabra1 Mutation Affects Cuticle Formation and Plant Responses to MicrobesPlant Physiology, 2010
- Activation of the Chloroplast Monogalactosyldiacylglycerol Synthase MGD1 by Phosphatidic Acid and PhosphatidylglycerolJournal of Biological Chemistry, 2010
- Phospholipase Dα1 and Phosphatidic Acid Regulate NADPH Oxidase Activity and Production of Reactive Oxygen Species in ABA-Mediated Stomatal Closure inArabidopsisTHE PLANT CELL ONLINE, 2009
- An Inositolphosphorylceramide Synthase Is Involved in Regulation of Plant Programmed Cell Death Associated with Defense inArabidopsisTHE PLANT CELL ONLINE, 2008
- Sphingolipid Long-Chain Base Hydroxylation Is Important for Growth and Regulation of Sphingolipid Content and Composition inArabidopsisTHE PLANT CELL ONLINE, 2008
- Mitochondrial Reactive Oxygen Species. Contribution to Oxidative Stress and Interorganellar SignalingPlant Physiology, 2006