Testing Toxicity and Antidote Effect of Selenium Nanoparticles with Paramecium caudatum
Open Access
- 1 January 2021
- journal article
- research article
- Published by Scientific Research Publishing, Inc. in Open Journal of Animal Sciences
- Vol. 11 (04), 532-542
- https://doi.org/10.4236/ojas.2021.114036
Abstract
A simple method for assessment of the toxicity and antidote effect of selenium nanoparticles with Paramecium caudatum is presented. Light microscopy in combination with computerized video tracking is employed for the determination of the survival time of P. caudatum. Up to 800 mg/L, selenium nanoparticles are not acutely toxic. With respect to a potential antidote effect, the lethality of silver nanoparticles, silver nitrate, sodium hydrogen selenite, and sodium selenite to P. caudatum was decreased and survival time was extended upon pre-treatment with selenium nanoparticles. Taken together, these findings suggest that administration of selenium nanoparticles attenuates exposure to toxicants. Selenium nanoparticles could be a good functional additive for food management in animals.Keywords
This publication has 37 references indexed in Scilit:
- Effect of sodium selenite, Se-yeast and nano-elemental selenium on growth performance, Se concentration and antioxidant status in growing male goatsSmall Ruminant Research, 2011
- Initial Study on the Toxicity of Silver Nanoparticles (NPs) against Paramecium caudatumThe Journal of Physical Chemistry C, 2009
- Elemental Selenium at Nano Size (Nano-Se) as a Potential Chemopreventive Agent with Reduced Risk of Selenium Toxicity: Comparison with Se-Methylselenocysteine in MiceToxicological Sciences, 2007
- Acute toxicity bioassay usingParamecium caudatum, a key member to study the effects of monocrotophos on swimming behaviour, morphology and reproductionToxicological & Environmental Chemistry, 2007
- Comparison of short-term toxicity between Nano-Se and selenite in miceLife Sciences, 2005
- Toxicity and Bioaccumulation of Hexavalent Chromium in Green Paramecium, Paramecium bursariaJournal of Health Science, 2005
- Effects of dietary selenium on glutathione peroxidase and thioredoxin reductase activity and recovery from cardiac ischemia–reperfusionJournal of Trace Elements in Medicine and Biology, 2004
- Two mechanisms of chemotaxis inParameciumJournal of Comparative Physiology A, 1978
- Bioelectric Control of Locomotion in the Ciliates*†The Journal of Protozoology, 1972
- Properties and biological activity of a new peptide antibiotic (Colisan)Biotechnology & Bioengineering, 1968