Virus Isolation from the First Patient with SARS-CoV-2 in Korea
Open Access
- 24 February 2020
- journal article
- research article
- Published by Korean Academy of Medical Sciences in Journal of Korean Medical Science
- Vol. 35 (7), e84
- https://doi.org/10.3346/jkms.2020.35.e84
Abstract
Novel coronavirus (SARS-CoV-2) is found to cause a large outbreak started from Wuhan since December 2019 in China and SARS-CoV-2 infections have been reported with epidemiological linkage to China in 25 countries until now. We isolated SARS-CoV-2 from the oropharyngeal sample obtained from the patient with the first laboratory-confirmed SARSCoV-2 infection in Korea. Cytopathic effects of SARS-CoV-2 in the Vero cell cultures were confluent 3 days after the first blind passage of the sample. Coronavirus was confirmed with spherical particle having a fringe reminiscent of crown on transmission electron microscopy. Phylogenetic analyses of whole genome sequences showed that it clustered with other SARS-CoV-2 reported from Wuhan.This publication has 13 references indexed in Scilit:
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