Multiresistance to Nonazole Fungicides in Aspergillus fumigatus TR 34 /L98H Azole-Resistant Isolates

Abstract
Drug resistance is a worldwide problem affecting all pathogens. The human fungal pathogen Aspergillus fumigatus coexists in the environment with other fungi targeted by crop protection compounds, being unintentionally exposed to the selective pressure of multiple antifungal classes and leading to the selection of resistant strains. A. fumigatus azole-resistant isolates are emerging in both clinical and environmental settings.
Funding Information
  • MEC | Instituto de Salud Carlos III (FIS PI18CIII/00045)
  • MEC | Instituto de Salud Carlos III (REIPI RD16/CIII/0004/0003)