Overweight and Obesity are Risk Factors for Coronavirus Disease 2019: A Propensity Score-Matched Case-Control Study
Open Access
- 28 February 2021
- journal article
- research article
- Published by Korean Endocrine Society in Endocrinology and Metabolism
- Vol. 36 (1), 196-200
- https://doi.org/10.3803/enm.2020.856
Abstract
Although obesity is a risk factor for infection, whether it has the same effect on coronavirus disease 2019 (COVID-19) need confirming. We conducted a retrospective propensity score matched case-control study to examine the association between obesity and COVID-19. This study included data from the Nationwide COVID-19 Registry and the Biennial Health Checkup database, until May 30, 2020. We identified 2,231 patients with confirmed COVID-19 and 10-fold-matched negative test controls. Overweight (body mass index [BMI] 23 to 24.9 kg/m(2); adjusted odds ratio [aOR], 1.16; 95% confidence interval [CI], 1.1.03 to 1.30) and class 1 obesity (BMI 25 to 29.9 kg/m(2); aOR, 1.27; 95% CI, 1.14 to 1.42) had significantly increased COVID-19 risk, while classes 2 and 3 obesity (BMI >= 30 kg/m(2)) showed similar but non-significant trend. Females and those < 50 years had more robust association pattern. Overweight and obesity are possible risk factors of COVID-19.Keywords
Funding Information
- Gachon University Gil Medical Center (2019-11)
- Korea Health Industry Development Institute
- Ministry of Health and Welfare (HI14C1135)
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