Maternity waiting home is one of the services that can be used to improve the health of pregnant women in order to reduce maternal mortality. The role of various stakeholders is needed so that this facility can be implemented properly. Stakeholders in the implementation are the government as policymakers and communities, especially pregnant women who are users of services and third parties who support the service of this service such as non-governmental organizations. This study examines regulation barriers in the implementation of maternity waiting homes in Wonogiri. Data collection is done by interviews and focuses on group discussions. The implementation of maternity waiting homes in the Wonogiri Regency has many obstacles, especially in terms of lack of regulation at the regional level. Support from various parties, especially strong political products in the form of a regulation in the regional area are important for the good implementation of the maternity waiting home in Wonogiri Regency.