Population Movement, City Closure in Wuhan, and Geographical Expansion of the COVID-19 Infection in China in January 2020
Open Access
- 17 April 2020
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical Infectious Diseases
- Vol. 71 (16), 2045-2051
- https://doi.org/10.1093/cid/ciaa422
Abstract
The unprecedented outbreak of 2019-nCoV pneumonia infection in Wuhan City caused global concern, the outflowing population from Wuhan was believed to be a main reason for the rapid and large-scale spread of the disease, so the government implemented a city closure measure to prevent its transmission considering the large amount of travelling before the Chinese New Year. Based on the daily reported new cases and the population movement data between January 1 and 31, we examined the effects of population outflow from Wuhan on the geographical expansion of the infection in other provinces and cities of China, as well as the impacts of the city closure in Wuhan in different scenarios of closing dates. We observed a significantly positive association between population movement and the number of the 2019-nCoV cases. The spatial distribution of cases per unit outflow population indicated that some areas with large outflow population might have been underestimated for the infection, such as Henan and Hunan provinces. Further analysis revealed that if the city closure policy was implemented two days earlier, 1420 (95% CI: 1059, 1833) cases could have been prevented, and if two days later, 1462 (95% CI: 1090, 1886) more cases would be possible. Our findings suggest that population movement might be one important trigger for the transmission of 2019-nCoV infection in China, and the policy of city closure is effective to control the epidemic.Keywords
Funding Information
- National Natural Science Foundation of China (82041021, 81803289)
- Prevention and Control of Infection Diseases (2017ZX10105011)
This publication has 18 references indexed in Scilit:
- New SARS-like virus in China triggers alarmScience, 2020
- The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health — The latest 2019 novel coronavirus outbreak in Wuhan, ChinaInternational Journal of Infectious Diseases, 2020
- Pneumonia of unknown aetiology in Wuhan, China: potential for international spread via commercial air travelJournal of Travel Medicine, 2020
- Population Movement Patterns Among the Democratic Republic of the Congo, Rwanda, and Uganda During an Outbreak of Ebola Virus Disease: Results from Community Engagement in Two Districts — Uganda, March 2019Morbidity and Mortality Weekly Report (MMWR), 2020
- Modeling Impact of Temperature and Human Movement on the Persistence of Dengue DiseaseComputational and Mathematical Methods in Medicine, 2017
- Risk of MERS importation and onward transmission: a systematic review and analysis of cases reported to WHOBMC Infectious Diseases, 2016
- Predicting the international spread of Middle East respiratory syndrome (MERS)BMC Infectious Diseases, 2016
- Empirical Evidence for the Effect of Airline Travel on Inter-Regional Influenza Spread in the United StatesPLoS Medicine, 2006
- Delaying the International Spread of Pandemic InfluenzaPLoS Medicine, 2006
- Forecast and control of epidemics in a globalized worldProceedings of the National Academy of Sciences of the United States of America, 2004