COVID-19 and liver cancer clinical trials: Not everything is lost
Open Access
- 1 July 2020
- journal article
- editorial
- Published by Wiley in Liver International
- Vol. 40 (7), 1541-1544
- https://doi.org/10.1111/liv.14532
Abstract
Since the first cases in Wuhan, China, during the month of December 2019, coronavirus disease (COVID‐19) evolved into a worldwide emergency, becoming one of the deadliest pandemics of modern history. As we write, the outbreak has led to 3,595,662 confirmed cases and 247,652 deaths worldwide1. SARS‐CoV‐2, the virus responsible for the disease, is a single‐stranded RNA virus which can cause a wide clinical spectrum of symptoms. According to the available knowledge, a large but still unknown percentage of the infected patients remains asymptomatic, representing an important and insidious vehicle of transmission2. According to the largest case series to date, most of the symptomatic patients complain of a mild respiratory syndrome (81%), while approximately 14% develop a severe disease requiring hospitalization and a further 5% need intensive care3.This publication has 13 references indexed in Scilit:
- Clinical characteristics of COVID-19-infected cancer patients: a retrospective case study in three hospitals within Wuhan, ChinaAnnals of Oncology, 2020
- SARS-CoV-2 Transmission in Patients With Cancer at a Tertiary Care Hospital in Wuhan, ChinaJAMA Oncology, 2020
- Between Scylla and Charybdis - Oncologic Decision Making in the Time of Covid-19The New England Journal of Medicine, 2020
- Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV-2)Science, 2020
- Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in ChinaJAMA, 2020
- COVID-19 and the liver: little cause for concernThe Lancet Gastroenterology & Hepatology, 2020
- Cancer patients in SARS-CoV-2 infection: a nationwide analysis in ChinaThe Lancet Oncology, 2020
- Cirrhosis-associated immune dysfunction: Distinctive features and clinical relevanceJournal of Hepatology, 2014
- Clinical impact of A/H1/N1/09 influenza in patients with cirrhosis: Experience from a nosocomial cluster of infectionJournal of Medical Virology, 2012
- Severe acute respiratory syndrome and the liverHepatology, 2004