Unravelling the health status of brachycephalic dogs in the UK using multivariable analysis
Open Access
- 14 October 2020
- journal article
- research article
- Published by Springer Science and Business Media LLC in Scientific Reports
- Vol. 10 (1), 1-13
- https://doi.org/10.1038/s41598-020-73088-y
Abstract
Brachycephalic dog breeds are regularly asserted as being less healthy than non-brachycephalic breeds. Using primary-care veterinary clinical data, this study aimed to identify predispositions and protections in brachycephalic dogs and explore differing inferences between univariable and multivariable results. All disorders during 2016 were extracted from a random sample of 22,333 dogs within the VetCompass Programme from a sampling frame of 955,554 dogs under UK veterinary care in 2016. Univariable and multivariable binary logistic regression modelling explored brachycephaly as a risk factor for each of a series of common disorders. Brachycephalic dogs were younger, lighter and less likely to be neutered than mesocephalic, dolichocephalic and crossbred dogs. Brachycephalic differed to non-brachycephalic types in their odds for 10/30 (33.33%) common disorders. Of these, brachycephalic types were predisposed for eight disorders and were protected for two disorders. Univariable and multivariable analyses generated differing inference for 11/30 (30.67%) disorders. This study provides strong evidence that brachycephalic breeds are generally less healthy than their non-brachycephalic counterparts. Results from studies that report only univariable methods should be treated with extreme caution due to potential confounding effects that have not been accounted for during univariable study design or analysis.Funding Information
- Kennel Club Charitable Trust
This publication has 76 references indexed in Scilit:
- Fashion vs. Function in Cultural Evolution: The Case of Dog Breed PopularityPLOS ONE, 2013
- Chronic Kidney Disease in Dogs in UK Veterinary Practices: Prevalence, Risk Factors, and SurvivalJournal of Veterinary Internal Medicine, 2013
- Neutering Dogs: Effects on Joint Disorders and Cancers in Golden RetrieversPLOS ONE, 2013
- The effect of neutering on the risk of urinary incontinence in bitches – a systematic reviewJournal of Small Animal Practice, 2012
- Assessing bias: the importance of considering confoundingEvidence-Based Spine-Care Journal, 2012
- Epidemiological research and evidence based medicine: How do they fit and for whomPreventive Veterinary Medicine, 2010
- Insurance data for research in companion animals: benefits and limitationsActa Veterinaria Scandinavica, 2009
- THE NORMALIZATION OF CORRUPTION IN ORGANIZATIONSResearch in Organizational Behavior, 2003
- The ecological fallacy strikes backJournal of Epidemiology and Community Health, 2000
- Craniofacial angle in dolicho-, meso- and brachycephalic dogs: radiological determination and applicationAnnals of Anatomy - Anatomischer Anzeiger, 1993