New 1,2,4-triazole/pyrazole hybrids linked to oxime moiety as nitric oxide donor celecoxib analogs: Synthesis, cyclooxygenase inhibition anti-inflammatory, ulcerogenicity, anti-proliferative activities, apoptosis, molecular modeling and nitric oxide release studies
- 12 March 2020
- journal article
- research article
- Published by Elsevier BV in Bioorganic Chemistry
- Vol. 98, 103752
- https://doi.org/10.1016/j.bioorg.2020.103752
Abstract
No abstract availableKeywords
This publication has 95 references indexed in Scilit:
- Systems Modeling of Anti-apoptotic Pathways in Prostate Cancer: Psychological Stress Triggers a Synergism Pattern Switch in Drug Combination TherapyPLoS Computational Biology, 2013
- OSU-A9 inhibits angiogenesis in human umbilical vein endothelial cells via disrupting Akt–NF-κB and MAPK signaling pathwaysToxicology and Applied Pharmacology, 2013
- Role of the Crosstalk between Autophagy and Apoptosis in CancerJournal of Oncology, 2013
- Erlotinib binds both inactive and active conformations of the EGFR tyrosine kinase domainBiochemical Journal, 2012
- Structure–Activity Relationships, Ligand Efficiency, and Lipophilic Efficiency Profiles of Benzophenone-Type Inhibitors of the Multidrug Transporter P-GlycoproteinJournal of Medicinal Chemistry, 2012
- The reemergence of nitric oxide and cancerNitric Oxide, 2008
- O2-Acetoxymethyl-protected diazeniumdiolate-based NSAIDs (NONO–NSAIDs): Synthesis, nitric oxide release, and biological evaluation studiesBioorganic & Medicinal Chemistry, 2007
- Cardiovascular Events Associated with Rofecoxib in a Colorectal Adenoma Chemoprevention TrialNew England Journal of Medicine, 2005
- Role of the Vascular Endothelial Growth Factor Pathway in Tumor Growth and AngiogenesisJournal of Clinical Oncology, 2005
- Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodMethods, 2001