Motor cortical thickness is related to effort-based decision-making in humans
- 6 May 2020
- journal article
- research article
- Published by American Physiological Society in Journal of Neurophysiology
- Vol. 123 (6), 2373-2381
- https://doi.org/10.1152/jn.00118.2020
Abstract
Although motor cortex is integral in driving physical exertion, how its inherent properties influence decisions to exert is unknown. In this study, we examined how anatomical properties of motor cortex are related to participants' subjective valuations of effort and their decisions to exert effort. We used computational modeling to characterize participants' subjective valuation of physical effort during an effort-based decision-making task in which they made choices about exerting different levels of hand-grip exertion. We also acquired structural MRI data from these participants, and extracted anatomical measures of each individual's hand knob, the region of motor cortex recruited during hand-grip exertion. We found that individual participants' cortical thickness of hand knob was associated with their effort-based decisions regarding hand exertion. These data provide evidence that the anatomy of an individual's motor cortex is an important factor in decisions to engage in physical activity.Keywords
Funding Information
- HHS | NIH | National Institute of Child Health and Human Development (K12HD073945)
- HHS | NIH | NICHD | National Center for Medical Rehabilitation Research (R01HD097619)
- HHS | NIH | National Institute of Mental Health (R56MH113627, R01MH119086)
- HHS | NIH | National Institute of General Medical Sciences (P41EB051909)
This publication has 55 references indexed in Scilit:
- Individual Differences in Premotor Brain Systems Underlie Behavioral ApathyCerebral Cortex, 2015
- The Effects of Incentive Framing on Performance Decrements for Large Monetary Outcomes: Behavioral and Neural MechanismsJournal of Neuroscience, 2014
- Changes in regional brain volume three months after strokeJournal of the Neurological Sciences, 2012
- MAOA-L carriers are better at making optimal financial decisions under riskProceedings. Biological sciences, 2010
- Cortical atrophy is relevant in multiple sclerosis at clinical onsetZeitschrift für Neurologie, 2007
- Delaunay Triangulation Based Surface ReconstructionPublished by Springer Science and Business Media LLC ,2006
- Neuroeconomics: How Neuroscience Can Inform EconomicsJournal of Economic Literature, 2005
- Changes in grey matter induced by trainingNature, 2004
- Alterations in the Thickness of Motor Cortical Subregions After Motor-Skill Learning and ExerciseLearning & Memory, 2002
- A simple algorithm for homeomorphic surface reconstructionPublished by Association for Computing Machinery (ACM) ,2000