Factors influencing lower respiratory tract infection in older patients after general anesthesia
Open Access
- 14 September 2021
- journal article
- research article
- Published by SAGE Publications in Journal of International Medical Research
- Vol. 49 (9)
- https://doi.org/10.1177/03000605211043245
Abstract
Objective: Pulmonary complication is common in older patients after surgery. We analyzed risk factors of lower respiratory tract infection after general anesthesia among older patients. Methods: In this retrospective investigation, we included older patients who underwent surgery with general anesthesia. Logistic regression analyses were performed to determine risk factors of lower respiratory tract infection. Results: A total 418 postoperative patients with general anesthesia were included; the incidence of lower respiratory tract infection was 9.33%. Ten cases were caused by gram-positive bacteria, 26 cases by gram-negative bacteria, and 2 cases by fungus. We found significant differences in age, smoking, diabetes, oral/nasal tracheal intubation, and surgery duration. Logistic regression analysis indicated that age ≥70 years (odds ratio [OR] 2.028, 95% confidence interval [CI] 1.115–3.646), smoking (OR 2.314, 95% CI 1.073–4.229), diabetes (OR 2.185, 95% CI 1.166–4.435), nasotracheal intubation (OR 3.528, 95% CI 1.104–5.074), and duration of surgery ≥180 minutes (OR 1.334, 95% CI 1.015–1.923) were independent risk factors of lower respiratory tract infections. Conclusions: Older patients undergoing general anesthesia after tracheal intubation have a high risk of lower respiratory tract infections. Clinical interventions should be provided to prevent pulmonary infections in patients with relevant risk factors.Keywords
Funding Information
- Natural Science Foundation of Xinjiang Uygur Autonomous Region (2019D01C305)
This publication has 57 references indexed in Scilit:
- Randomized comparison of experts and trainees with nasal and oral fibreoptic intubation in children less than 2 yr of ageBritish Journal of Anaesthesia, 2015
- Ventilator-Associated Pneumonia in Newborn Infants Diagnosed With an Invasive Bronchoalveolar Lavage TechniquePediatric Critical Care Medicine, 2013
- Antibiotic-resistant bacteria and infection in children with cerebral palsy requiring mechanical ventilationPediatric Critical Care Medicine, 2009
- Mechanical Ventilation in an Airborne EpidemicClinics in Chest Medicine, 2008
- The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studiesJournal of Clinical Epidemiology, 2008
- Ventilator-associated pneumonia caused by multidrug-resistant organisms or Pseudomonas aeruginosa: Prevalence, incidence, risk factors, and outcomesJournal of Critical Care, 2008
- The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: Guidelines for Reporting Observational StudiesAnnals of Internal Medicine, 2007
- The circulatory responses to tracheal intubation in children: a comparison of the oral and nasal routesAnaesthesia, 2007
- Mechanical ventilation and lung infection in the genesis of air-space enlargementCritical Care, 2007
- Influence of long-term oro- or nasotracheal intubation on nosocomial maxillary sinusitis and pneumoniaCritical Care Medicine, 1993