Delayed urticaria or anaphylaxis after consumption of red meat with evidence of alpha-gal sensitisation
- 28 December 2020
- journal article
- research article
- Published by BMJ in BMJ Case Reports
- Vol. 13 (12), e236923
- https://doi.org/10.1136/bcr-2020-236923
Abstract
Food allergies to red meat, specifically to galactose-alpha-1,3-galactose (alpha-gal), a mammalian oligosaccharide, are considered to be very rare, especially in Asia and Latin America. Most of the cases reported are characterised by symptoms of delayed urticaria or anaphylaxis after the consumption of red meat. Sensitisation to red meat has been linked to the use of cetuximab or tick bites, especially from the Amblyomma americanum and Ixodes spp species. Here, we documented a case study from a Colombian male patient with symptoms of delayed urticaria and anaphylaxis with a history of tick bites in Colombia. The patient presented with IgE antibodies specific to alpha-gal, which is the most common epitope linked to red meat allergy induced by tick bites.Keywords
This publication has 18 references indexed in Scilit:
- Amblyomma sculptum tick saliva: α-Gal identification, antibody response and possible association with red meat allergy in BrazilInternational Journal for Parasitology, 2016
- Delayed anaphylaxis to alpha-gal, an oligosaccharide in mammalian meatAllergology International, 2015
- Mammalian meat allergy: a diagnostic challengeAllergo Journal International, 2015
- Delayed Anaphylaxis Involving IgE to Galactose-alpha-1,3-galactoseCurrent Allergy and Asthma Reports, 2015
- The alpha-gal story: Lessons learned from connecting the dotsJournal of Allergy and Clinical Immunology, 2015
- Tick-induced allergies: mammalian meat allergy, tick anaphylaxis and their significanceAsia Pacific Allergy, 2015
- Delayed Anaphylaxis to Red Meat Associated With Specific IgE Antibodies to GalactoseAllergy, Asthma & Immunology Research, 2015
- Delayed Anaphylaxis to Red Meat Masquerading as Idiopathic AnaphylaxisThe Journal of Allergy and Clinical Immunology: In Practice, 2014
- A Peculiar Cause of Anaphylaxis: No More steak?Journal of General Internal Medicine, 2012
- Clinical features and severity grading of anaphylaxisJournal of Allergy and Clinical Immunology, 2004