Surgical Results for Infective Endocarditis Complicated With Cardiogenic Shock
- 25 May 2020
- journal article
- research article
- Published by Japanese Circulation Society in Circulation Journal
- Vol. 84 (6), 926-934
- https://doi.org/10.1253/circj.cj-19-0583
Abstract
Background:Infective endocarditis remains associated with substantial mortality and morbidity rates, and the presence of acute heart failure (AHF) compromises clinical results after valve surgery; however, little is known in cardiogenic shock (CGS) patients. This study evaluated the clinical results and risk of mortality in CGS patients after valve surgery. Methods and Results:This study enrolled 585 patients who underwent valve surgery for active endocarditis at 14 institutions between 2009 and 2017. Of these patients, 69 (12%) were in CGS, which was defined as systolic blood pressure Staphylococcus aureusinfection (odds ratio [OR] 2.19; P=0.044), double valve involvement (OR 3.37; P=0.003), and larger vegetation (OR 1.05; P=0.036) were risk factors for CGS. Hospital mortality occurred in 27 (13%) non-CGS AHF patients and in 15 (22%) CGS patients (P=0.079). Overall survival at 1 and 5 years in CGS patients was 76% and 69%, respectively, and there were no significant differences in overall survival compared with non-CGS AHF patients (P=1.000). Conclusions:Clinical results after valve surgery in CGS patients remain challenging; however, mid-term results were equivalent to those of non-CGS AHF patients.Keywords
This publication has 20 references indexed in Scilit:
- Speckle tracking echocardiography as a new technique to evaluate right ventricular function in patients with left ventricular assist device therapyThe Journal of Heart and Lung Transplantation, 2013
- Incidence, risk factors and prediction of post-operative acute kidney injury following cardiac surgery for active infective endocarditis: an observational studyCritical Care, 2013
- Emergency Surgery for Native Mitral Valve Endocarditis: The Impact of Septic and Cardiogenic ShockThe Annals of Thoracic Surgery, 2012
- Association Between Valvular Surgery and Mortality Among Patients With Infective Endocarditis Complicated by Heart FailureJAMA, 2011
- Outcomes for endocarditis surgery in North America: A simplified risk scoring systemThe Journal of Thoracic and Cardiovascular Surgery, 2011
- Costs and outcomes of acute kidney injury (AKI) following cardiac surgeryNephrology Dialysis Transplantation, 2008
- Acute kidney injury prediction following elective cardiac surgery: AKICS ScoreKidney International, 2007
- Early Surgery in Patients with Infective Endocarditis: A Propensity Score AnalysisClinical Infectious Diseases, 2007
- Early Predictors of In-Hospital Death in Infective EndocarditisCirculation, 2004
- Proposed Modifications to the Duke Criteria for the Diagnosis of Infective EndocarditisClinical Infectious Diseases, 2000