Rapid and sensitive detection of neotame in instant grain beverages by paper-based silver nanoparticles substrates
- 30 December 2020
- journal article
- research article
- Published by Institution of Engineering and Technology (IET) in Micro & Nano Letters
- Vol. 15 (15), 1099-1104
- https://doi.org/10.1049/mnl.2020.0298
Abstract
Neotame is an artificial sweetener with increasing consumption in recent years, excessive intake of it may bring potential health risk. In this work, a rapid method was developed to detect neotame in instant grain beverages, which was based on surface-enhanced Raman scattering (SERS) technique and filter paper-based silver nanoparticles (AgNPs@FP) substrates. The designed substrate exhibits good SERS activity with an enhancement factor of 10(5) because of the synergistic effect of the concentrated silver nanoparticles and filter paper. Meanwhile, the stability and repeatability of this fabricated substrate have been investigated with the relative standard deviation of 6.1%. In addition, it shows an excellent linear relationship (R-2 = 0.997) between the SERS signal and the logarithm concentration of neotame with a wide concentration range (0.05-5 g/kg) in the quantitative analysis. The limit of detection of neotame can be as low as 0.01 g/kg in instant grain beverages, which is below the maximum allowable addition level for neotame in instant grain beverages set in China (GB2760-2014, 0.16 g/kg). The proposed method has great potential for the identification and quantification of neotame in food safety applications with high sensitivity.Funding Information
- National Natural Science Foundation of China (21305163)
This publication has 27 references indexed in Scilit:
- Shaped-controlled electrosynthesis of gold nanodendrites for highly selective and sensitive SERS detection of formaldehydeSensors and Actuators B: Chemical, 2014
- Chemical mapping of a single molecule by plasmon-enhanced Raman scatteringNature, 2013
- Determination of neotame in non-alcoholic beverage by capillary zone electrophoresisJournal of the Science of Food and Agriculture, 2013
- HPLC-MS/MS analysis of 9 artificial sweeteners in imported foodsFood Science and Biotechnology, 2013
- A silver nanoparticle based surface enhanced resonance Raman scattering (SERRS) probe for the ultrasensitive and selective detection of formaldehydeNanoscale, 2012
- Highly Sensitive Surface Enhanced Raman Scattering Substrates Based on Filter Paper Loaded with Plasmonic NanostructuresAnalytical Chemistry, 2011
- The ORCA program systemWIREs Computational Molecular Science, 2011
- Determination of neotame in beverages, cakes and preserved fruits by column-switching high-performance liquid chromatographyFood Additives & Contaminants: Part A, 2010
- Simultaneous determination of nine intense sweeteners in foodstuffs by high performance liquid chromatography and evaporative light scattering detection—Development and single-laboratory validationJournal of Chromatography A, 2007
- Adsorption and surface-enhanced Raman of dyes on silver and gold solsThe Journal of Physical Chemistry, 1982