Magnetization‐prepared GRASP MRI for rapid 3D T1 mapping and fat/water‐separated T1 mapping
- 13 February 2021
- journal article
- research article
- Published by Wiley in Magnetic Resonance in Medicine
- Vol. 86 (1), 97-114
- https://doi.org/10.1002/mrm.28679
Abstract
Purpose This study aimed to (i) develop Magnetization‐Prepared Golden‐angle RAdial Sparse Parallel (MP‐GRASP) MRI using a stack‐of‐stars trajectory for rapid free‐breathing T1 mapping and (ii) extend MP‐GRASP to multi‐echo acquisition (MP‐Dixon‐GRASP) for fat/water‐separated (water‐specific) T1 mapping. Methods An adiabatic non‐selective 180° inversion‐recovery pulse was added to a gradient‐echo‐based golden‐angle stack‐of‐stars sequence for magnetization‐prepared 3D single‐echo or 3D multi‐echo acquisition. In combination with subspace‐based GRASP‐Pro reconstruction, the sequence allows for standard T1 mapping (MP‐GRASP) or fat/water‐separated T1 mapping (MP‐Dixon‐GRASP), respectively. The accuracy of T1 mapping using MP‐GRASP was evaluated in a phantom and volunteers (brain and liver) against clinically accepted reference methods. The repeatability of T1 estimation was also assessed in the phantom and volunteers. The performance of MP‐Dixon‐GRASP for water‐specific T1 mapping was evaluated in a fat/water phantom and volunteers (brain and liver). Results ROI‐based mean T1 values are correlated between the references and MP‐GRASP in the phantom (R2 = 1.0), brain (R2 = 0.96), and liver (R2 = 0.73). MP‐GRASP achieved good repeatability of T1 estimation in the phantom (R2 = 1.0), brain (R2 = 0.99), and liver (R2 = 0.82). Water‐specific T1 is different from in‐phase and out‐of‐phase composite T1 (composite T1 when fat and water signal are mixed in phase or out of phase) both in the phantom and volunteers. Conclusion This work demonstrated the initial performance of MP‐GRASP and MP‐Dixon‐GRASP MRI for rapid 3D T1 mapping and 3D fat/water‐separated T1 mapping in the brain (without motion) and in the liver (during free breathing). With fat/water‐separated T1 estimation, MP‐Dixon‐GRASP could be potentially useful for imaging patients with fatty‐liver diseases.This publication has 72 references indexed in Scilit:
- Compressed sensing for body MRIJournal of Magnetic Resonance Imaging, 2016
- Towards Routine Clinical Use of Radial Stack-of-Stars 3D Gradient-Echo Sequences for Reducing Motion SensitivityJournal of the Korean Society of Magnetic Resonance in Medicine, 2014
- Golden‐angle radial sparse parallel MRI: Combination of compressed sensing, parallel imaging, and golden‐angle radial sampling for fast and flexible dynamic volumetric MRIMagnetic Resonance in Medicine, 2013
- Respiratory self‐navigation for whole‐heart bright‐blood coronary MRI: Methods for robust isolation and automatic segmentation of the blood poolMagnetic Resonance in Medicine, 2011
- Free-Breathing Radial 3D Fat-Suppressed T1-Weighted Gradient Echo SequenceInvestigative Radiology, 2011
- Respiratory and cardiac self‐gated free‐breathing cardiac CINE imaging with multiecho 3D hybrid radial SSFP acquisitionMagnetic Resonance in Medicine, 2010
- Acquisition and reconstruction of undersampled radial data for myocardial perfusion magnetic resonance imagingJournal of Magnetic Resonance Imaging, 2009
- Undersampled radial MRI with multiple coils. Iterative image reconstruction using a total variation constraintMagnetic Resonance in Medicine, 2007
- Self‐gated cardiac cine MRIMagnetic Resonance in Medicine, 2003
- Projection Reconstruction Techniques for Reduction of Motion Effects in MRIMagnetic Resonance in Medicine, 1992