The coexistence of students in the classroom from different cultural backgrounds is a challenge. Literature as a cultural product may contribute to the cultivation of intercultural empathy and acceptance of diversity in various ways. This study examines how literature may contribute to the treatment of issues related to stereotypes, gender discrimination, and how it may eliminate prejudices in the classroom. Initially, through the bibliographic review, the effect of literature on the psycho-emotional development of the individual, the strengthening of resilience and on the development of emotional intelligence is investigated as a key element for the development of healthy interpersonal relationships. Then, this study presents the results of an action research that utilized literature to break stereotypes in a pluralistic class. The action research took place at schools in Chania (Crete, Greece), and it highlights the empathic function of literature in removing stereotypes and discrimination in the classroom through various experiential activities and cooperative role play. Literature cultivates empathy and students may get into “others' shoes’’, accepting diversity. Through structured literature-based programs, a teacher may cultivate intercultural understanding and empathy, promoting human rights and enhancing the learners as future citizens with an inclusive and humanitarian attitude.