Bacteriological pattern of urinary tract infection in men with symptomatic benign prostatic hyperplasia at a tertiary hospital in Nigeria
- 29 October 2022
- journal article
- Published by Peertechz Publications Private Limited in Journal of Biology and Medicine
- Vol. 6 (1), 024-028
- https://doi.org/10.17352/jbm.000032
Abstract
Introduction/Background: Benign Prostatic Hyperplasia (BPH) is characterized by narrowing of the prostatic urethra with resultant difficulty in passing urine, stasis, and a predisposition to urinary tract infection. The objective of this study is to identify the prevalence of urinary tract infections, common organisms isolated, their antimicrobial sensitivity pattern, and the relationship of co-morbidities with urinary tract infection in this population. Materials and methods: All patients who presented to our urology team with bladder outlet obstruction secondary to benign prostatic hyperplasia between January 2020 and January 2021 were included. Information on age, occupation, co-morbid conditions, urine microscopy, culture, and sensitivity patterns were obtained and analyzed using SPSS version 25. Midstream urine samples were collected from 172 BPH patients. Microscopy, culture, and antibiotic susceptibility tests were carried out. Results: From our study, the prevalence of bacteriuria was 67.9% with the 65-74 and 45-54 age groups having the highest and the least prevalence of bacteriuria (88.9% and 33.3% respectively). The most common organisms cultured from their urine were Pseudomonas (17.9%), E. coli (14.3%), Coliforms (10.7%), and Klebsiella (10.7%). Sensitivity patterns of these microorganisms revealed the highest sensitivity to the fluoroquinolones (25.9%) followed by Nitrofurantoin (14.8%) and Ceftriaxone and Cefoxitin (7.4%). The least sensitivity was to Augmentin and Gentamycin. Conclusion: Bacteriuria is common in patients with BPH. Pseudomonas spp was the commonest isolated organism in our study and most isolated organisms were susceptible to the fluoroquinolones.Keywords
This publication has 11 references indexed in Scilit:
- Lower Urinary Tract Infections among Patients Diagnosed of Benign Prostate Hyperplasia in Federal Medical Centre, Bida, North Central, NigeriaBritish Journal of Medicine and Medical Research, 2016
- Bacteriology of urine specimens obtained from men with symptomatic benign prostatic hyperplasiaNigerian Journal of Surgery, 2016
- Bacterial Uropathogen among Benign Prostatic Hyperplasia Patients at a Tertiary Hospital in NigeriaOpen Journal of Medical Microbiology, 2015
- How to Calculate Sample Size for Different Study Designs in Medical Research?Indian Journal of Psychological Medicine, 2013
- Prevalence of histological prostatitis in men with benign prostatic hyperplasia or adenocarcinoma of the prostate presenting without urinary retentionSouth African Journal of Surgery, 2012
- Seven months retrospective study on Urinary Tract Infection among patients at Aminu Kano Teaching Hospital, Kano - NigeriaBayero Journal of Pure and Applied Sciences, 2011
- Catheter associated urinary tract infection: Aetiologic agents and antimicrobial susceptibility pattern in Ladoke Akintola University Teaching Hospital, Osogbo, NigeriaAfrican Journal of Biomedical Research, 2009
- Risk factors and comorbid conditions associated with lower urinary tract symptoms: EpiLUTSBJU International, 2009
- ANTIBIOTIC PROPHYLAXIS FOR TRANSURETHRAL PROSTATIC RESECTION IN MEN WITH PREOPERATIVE URINE CONTAINING LESS THAN 100,000 BACTERIA PER ML: A SYSTEMATIC REVIEWJournal of Urology, 2005
- Nosocomial infections: urinary tract infection in patients with indwelling urinary catheterAfrican Journal of Clinical and Experimental Microbiology, 2003