Open Journal of Orthopedics and Rheumatology

Journal Information
EISSN: 26413116
Total articles ≅ 60

Latest articles in this journal

Gonzalez Enriquez Jose Octavio, , Herrera Van Oostdam David Alejandro
Open Journal of Orthopedics and Rheumatology, Volume 8, pp 008-012;

Antisynthetase Syndrome (ASS) is a rare chronic autoimmune disorder, associated with interstitial lung diseases (the most important feature), such as Dermatomyositis (DM) and Polymyositis (PM). The cause of ASS is unknown. The hallmark of ASS is the presence of serum autoantibodies directed against aminoacyl-tRNA synthetases (anti-ARS involved in protein synthesis). Anti -Jo1 is the most common (20% - 30%); anti-PL12 is present in 2% - 5% of SAS, associated with Interstitial Lung Disease (ILD) in 90%, mainly as Non-Specific Interstitial Pneumonia (NSIP). Autoimmune hepatitis is related to rheumatological diseases (2.7% - 20% in systemic lupus erythematosus, 6% - 47% in primary Sjögren’s syndrome), however, is rare in patients with inflammatory myopathies, and there is no previous reported association with SAS. A literature search was carried out using the PubMed and EMBASE databases in English and Spanish. Our case, a 62-year-old woman who developed polyarthritis, with progressive dyspnea, facial and lower limb edema, proximal muscle weakness, and Raynaud’s phenomenon; high-resolution chest CT, showing pulmonary interstitial disease, consistent with Nonspecific Interstitial Pneumonia (NSIP). She had elevated transaminases and a prolonged prothrombin time, with positive anti-nuclear and anti-smooth muscle antibodies, and was made a diagnosis with autoimmune hepatitis type 1 (HAI). According to this presentation and reports of the literature review, anti-PL12 patients are characteristically associated with a severe phenotype of lung inflammation, that does not necessarily require myositis manifestation. To our knowledge, there is not any case of the antisynthetase syndrome and autoimmune hepatitis reported previously in the literature.
Magalov Sh I, Huseynova Sadagat, Mustafaeva Ee, Bagirova R
Open Journal of Orthopedics and Rheumatology, Volume 8, pp 001-007;

Introduction: Carpal Tunnel Syndrome (CTS) is the most common and best well-known cause of peripheral nerve compression. To date, none of the studies have determined the optimal combination of pyrimidine nucleotides and electrical stimulation (ES) in CTS patients. The objective of the study was to evaluate the effectiveness of a novel product containing uridine and cytidine monophosphate (Nucleo CMP Forte™) in combination with ES for the treatment of CTS. Methods: This open-label, randomized, controlled study involved 60 patients with CTS at the Azerbaijan Medical University (Baku, Azerbaijan) and Research Institute of Medical Rehabilitation between 2017 and 2021 years. Patients were randomized to receive the exploratory treatment (Nucleo CMP Forte™ and ES) or single ES treatment for ten days. The combination treatment included two stages: Nucleo CMP Forte™ and ES for ten days (stage one), and Nucleo CMP Forte™ as monotherapy (stage two) for ten days. Results: In the exploratory group, the complete restoration of pain sensitivity was achieved by 17.1% of patients and the narrowing of the existing zone of hypesthesia by 74.3%. Positive Tinel test was revealed in 52.4% of patients after the first and 76.2% after the second stage in the exploratory group, versus 43.8% in the control group. Mean values in the Boston Carpal Tunnel Questionnaire significantly decreased in both groups. Conclusion: Nucleo CMP Forte™ in combination with ES contributes to a more pronounced regression of patients' complaints, clinical manifestations, severity, and neurophysiological indicators in mild-to-moderate CTS.
Zhukov Kirill V, Gasparyan Bagrat A, Vetcher Alexandre A, Shishonin Alexander Y
Open Journal of Orthopedics and Rheumatology, Volume 7, pp 011-012;

For over four centuries the posture was under very different points of view. The theory of centralized Aerobic-Anaerobic Energy Balance Compensation (CAAEBC) gives an additional angle of consideration, associated with the concept of brachiocephalic arterial blood flow access to the rhomboid fossa. This helps to understand the requirements of the set of physical exercises, that will be able to keep the posture training simultaneously with the healthcare.
Mokhchani Youness, Rachdi Abderrafia, Rabbah Abdelhay, Boukhriss Jalal, Chafry Bouchaib, Boussouga Mustapha
Open Journal of Orthopedics and Rheumatology, Volume 7, pp 004-007;

Chondrosarcoma is a malignant tumor occupying the 2nd position in terms of frequency, all ages combined, after osteosarcoma [1]. Epidemiological data extracted from cancer registries in Europe indicate an annual incidence of ~0.1/100,000 inhabitants [2]. Mesenchymal chondrosarcoma of bone is a rare high-grade variant of chondrosarcoma (2-13%), which usually has an extra-skeletal (30-40%) or central intramedullary location (15-30%).
Mawella R, RajaK R
Open Journal of Orthopedics and Rheumatology, Volume 7, pp 001-003;

Osteoporosis is a skeletal disorder characterized by compromised bone strength resulting in an increased risk of fracture [1]. Bone Mineral Density (BMD) is responsible for 60-90% of the strength of bone [1] and the current standard of assessment is by Dual-energy X-Ray Absorptiometry (DXA). DXA generates T-scores of the lumbar spine, femoral neck, or hip by calculating the difference between the individual’s BMD and the population mean, divided by the standard deviation of the reference population. The World Health Organisation (WHO) classifies osteoporosis at a T-score of or below -2.5.
Ali Aadil Ameer, Bhutto Natasha, Chandio Shahmeer, Waqas Shoaib, Khoso Ali Raza, Rafique Muhammad, Ismail Muhammad, Iqbal Shanza
Open Journal of Orthopedics and Rheumatology pp 062-066;

, Dixit Hrudini, Mistry Tuhin, Balavenkatasubramanian J
Open Journal of Orthopedics and Rheumatology, Volume 6, pp 046-056;

The modernization of arthroplasty has paved the way for the resurgence of ultrasound-guided regional analgesia (RA) techniques. The evolution of newer RA techniques aids in reducing postoperative pain considerably as well as facilitates early ambulation and discharge.
, Chaves de Resende Rogerio Lucio, Ghedini Daniel Ferreira, Vital Leandro Vinicius, de Freitas Junior Haroldo Oliveira, Teixeira Luiz Eduardo Moreira
Open Journal of Orthopedics and Rheumatology, Volume 6, pp 030-036;

The clavicle is the most frequently fractured bone in humans. General anesthesia with or without Regional Anesthesia (RA) is most frequently used for clavicle surgeries due to its complex innervation.
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