A healthy Caucasian female neonate was born at 38 weeks and 3 days of gestation by elective cesarean delivery. She is the second child of a healthy mother, had a proper antenatal follow-up, and had no fetal anomalies in prenatal ultrasounds.

Building on the concept of “Autism Spectrum Disorder”, as framed in the DSM-V, and taking up studies on the new etiological theory (PETA) focusing on the developmental model of the neurobiological matrix (PEMA) and related questionnaire (PTAS-Qa), in this research a new questionnaire is proposed that can focus on the presence or absence of 4 functional areas (interactional and movement, language, and communication, ideational and social, emotional and behavioral) and 25 type-deficit traits, grading the impairment according to a precise 5-level severity scale (PASSy). The new questionnaire (Perrotta Autism Spectrum Disorders Questionnaire for infants and young adolescents, PASD-Qy), is composed of 25 items, on a binary S/N scale and based on a total score of 10/10, for a population between 18 months and < 16 years, thus offering a structured view of the individual’s cognitive organization, avoiding diagnostic fragmentations that might be inconsistent with the nosographic framework. By exemplifying the category, it is then possible to more easily frame the patient, who would thus be analyzed from a strictly functional point of view, also facilitating the preparation of therapeutic interventions, according to models already known in the literature (e.g., ABA), exactly as for the questionnaire dedicated to late adolescents and adults.

Objective: Pediatric Intensive Care (PICU) admission of children with bronchiolitis as well as the use of Non-Invasive Ventilation (NIV) are increasing. The current treatment for bronchiolitis is supportive, and there are no specific studies addressing this group of severe bronchiolitis patients supported with NIV. Intrapulmonary Percussive Ventilation (IPV) is a lung recruitment physical therapy technique used in our PICU to augment lung aeration and improve gas exchange. We hypothesized that IPV treatment can be used to improve the clinical course of infants on NIV support suffering from bronchiolitis. Design: A prospective, open, randomized study. Setting: Single-center Pediatric ICU Patients: Children less than 2 years old admitted to our PICU between November 2016 and April 2018 with a diagnosis of bronchiolitis who were prescribed noninvasive positive pressure ventilation as their sole respiratory treatment modality Interventions: Patients were randomly assigned to two intervention groups: IPV vs. control (standard treatment). Measurements and main results: Thirty-eight infants with bronchiolitis treated with NIV support were randomized into two groups. The probability of a superior outcome (less chance of invasive mechanical ventilation and fewer PICU days) was 62.7% (95% CI, 45%-77%, p = 0.18) in the IPV group compared to the control group. Among the IPV group, there were no failures that required intubation in comparison to three intubations (13.6%) among the control group (p = 0.24). For the IPV group, the PICU length of stay (LOS) was 4.13 ± 2.45 days, compared to 6.18 ± 4.72 for the inhalation group. This difference was not statistically significant. Conclusions: In this single-center study, the use of IPV had no adverse reactions. The study failed to show a statistically significant effect of IPV treatment on the course of hospitalization of patients with bronchiolitis on NIV support in the PICU. Trial registration: Clinical Trials.gov NCT03037801.

Starting from the concept of “Autism Spectrum Disorder”, as framed in the DSM-V, the present research proposes a new etiological theory (PETA) focused on the evolutionary model of the neurobiological matrix, overcoming the modest or inconsistent psychodynamic or conspiracy theses present in the international scene. Based on this assumption, therefore, a new study model (PEMA) was suggested that can focus on the presence or absence of 9 dysfunctional traits (type-deficit and type-clinical features) centered on the areas of social, emotional, and cognitive-communication and interaction, grading the impairment according to a precise 5-level severity scale (PASS), underpinning the 40-item questionnaire (Perrotta Dysfunctional Traits of the Autistic Spectrum Questionnaire for the late teenage years and Adults, PTAS-Qa) on a binary Y/N scale and based on a total score of 11/11, thus offering a more structured view of the patient’s cognitive and psychological organization, avoiding diagnostic fragmentations that might be inconsistent with the nosographic picture and therefore not perfectly framed. By exemplifying the category, it is, therefore, possible to more easily frame the patient, who would thus be analyzed from a strictly functional point of view, also facilitating the therapeutic interventions to be prepared, according to models already known in the literature (e.g. ABA).

The outgrowth and quick development in telecommunication technologies have opened new opportunities for diagnosing many diseases, which are life-threatening, for patients who are in rural areas and districts far away from the city, and where there are no specialists. Critical and life-threatening diseases, in which the patient cannot wait until going to a central hospital, or specialist, need to benefit from the advantages of telecommunication technologies to save the patient’s life. The segment of pediatric patients represents a significant number of patients and children represent the country’s present and bright future, so we must focus on the importance of diagnosing and treating their diseases early and on a time using the ways and means available to protect their lives from risks. Designing a tele-pediatric system for monitoring such cases can be vital and efficient in saving those babies’ lives and protecting them from significant risks of disability and even death that happen if their defects are not diagnosed and treated soon after birth. This project aimed to design a tele-pediatric system, using webpages at both transmitting and receiving sites and connected to a united database and then linked with the Sudan University of Science and Technology’s Network for testing its efficiency and effectiveness. If this project is applied; it will contribute to saving the baby’s life and raise the overall health care.

Dysgraphia is defined as the difficulty in the production of written language. This study was carried out on 50 subjects aged 6-12 years who suffered from writing disabilities. This methodological study was designed to measure the possible breakdown mechanisms causing dysgraphia. A scale was created to cover most of the weak points in dysgraphia especially the fine motor and proprioceptive aspects. Reliability and validity of this scale were performed to allow its application. Findings were dealt with statistically and it was found that three types of dysgraphia have been known as Dyslexic, Motoric, and Spatial Dysgraphia. The scale diagnoses dysgraphia in an objective way and the severity of the condition can be determined in addition. This helps better understand the patients’ needs when a trainer designs the remediation program.

Objective: To evaluate the effectiveness of Physical Therapy Management among the toe walking children’s in Karachi Pakistan. Methodology: A cross sectional survey was conducted from June to October 2018 in Department of physiotherapy, Liaquat National medical college and hospital, Karachi, Pakistan. A self-fabricated questionnaire was used in 36 Toe walking children’s. The questionnaire consists of demographics (age and gender), evaluation of pain through visual analogue scale, range of motion through goniometer and cadence was measured .The statistical package for social sciences (SPSS) version 23 was used to interpret the data. Result: The majority (n=24, 66.6%) were belongs to age group of 8 to 12 years and (n=25, 69.4%) were male. Mostly (n=25, 69.4%) were clinically diagnosed cases of cerebral palsy. After checking the involvement it was found that (n=21, 58.3%) were suffering from bilateral toe walking and (n=22, 61.1%) were affected from the day of their birth. Conclusion: The study finalized that the Physical Therapy is effective in decreasing the pain, increasing the range of motion and improving the number of steps among the toe walking children’s.