Indian Journal of Clinical and Experimental Ophthalmology

Journal Information
ISSN / EISSN: 23951443 / 23951451
Total articles ≅ 780

Latest articles in this journal

Tejinder Kaur Walia, Manoj Gupta, Ruminder Kaur
Indian Journal of Clinical and Experimental Ophthalmology, Volume 8, pp 500-503; https://doi.org/10.18231/j.ijceo.2022.101

Abstract:
Pseudoexfoliation syndrome is a multifactorial diffuse disease and is diagnosed clinically on slit lamp examination of the eye by the deposition of white, dandruff like material on different structures in anterior segment i:e corneal endothelium, iris, pupillary margin, anterior lens capsule, zonules and trabecular meshwork. The aim of study was to study demographic features, intraoperative and postoperative complications and the visual outcome of cataract surgery in pseudoexfoliation patients. 93 eyes of 93 patients with pseudoexfoliation posted for cataract surgery were included in the study. 79.56% patients were of more than 60 years of age group.43 patients were male and 50 patients were female. 44 patients had pseudoexfoliation syndrome in both eyes and 49 patients had either right eye or left eye involvement. Intraoperative problems encountered were poor pupillary dilatation, capsular bag prolapse, zonular dehiscence, posterior capsular rent, residual cortical matter and positive vitreous pressure. Postoperative complications reported were corneal edema, raised intraocular pressure, significant anterior chamber cell reaction, left cortical matter and exudative membrane. Best corrected visual acuity was more than 6/18 in 67 eyes, between 6/60-6/24 in 16 eyes, and less than 6/60 in 10 eyes. At 1 month, best corrected visual acuity was more than 6/18 in 92 eyes. Cataract surgery in pseudoexfoliation patients is associated with high risk of complications. Use of iris hooks and capsule tension rings where required during the surgery can decrease the intraoperative complications and thus will give better visual outcome.
Shefali Mazumdar, Saran Kumar Satsangi, Rajiv Kumar Pandey, Nishi Dwivedi, Oshin Malhotra
Indian Journal of Clinical and Experimental Ophthalmology, Volume 8, pp 474-480; https://doi.org/10.18231/j.ijceo.2022.096

Abstract:
Evaluation of success rate of manual DSEK in terms of central corneal thickness and BSCVA in patients of PBK. : Prospective, non-comparative, interventional study of 18 patients of PBK, who underwent manual DSEK between June 2021 to May 2022 with minimum six months to maximum 15 months post-operative follow up. DSEK lenticule was prepared by manual dissection. Push in technique with 26 G needle was used for graft insertion. Preoperative and post-operative CCT and BSCVA were measured and compared. : Preoperative central pachymetry in patients (n=18) was (832±162) μm which significantly reduced in the post operative period. The mean thickness of lenticule on day 1 post op was 203±93.5μm which became 156±76 μm (p =.0436) at 6 months and remained almost same till last follow up. Pre operative BSCVA ranged from HM to 2/60 in these 18 patients which was improved in 16/18 eyes post DSEK. Eighty eight percent (15/17) patients had regained BSCVA of 6/60 to 6/12. In early post operative period, complications noted were, partial detachment of lenticule and pupillary block glaucoma which were managed accordingly.: Manual DSEK is feasible, low-cost widely accessible alternative to DSAEK/DMEK for patients of PBK with good visual outcome in resource limited settings.: Manual DSEK has short learning curve and it’s training should be imparted to corneal surgeons for better outcome in PBK and other causes of endothelial decompensation.
Priyanka Patel, Yamini Rawate
Indian Journal of Clinical and Experimental Ophthalmology, Volume 8, pp 481-486; https://doi.org/10.18231/j.ijceo.2022.097

Abstract:
To analyze different ophthalmic manifestations of rhino-orbital mucormycosis (ROM) infection in COVID-19 patients. Prospective interventional clinical study.20 microbiologically confirmed ROCM cases with ophthalmic involvement hospitalized between May 2021 and July 2021 in our center were included in this study. Among 20 cases there were 9 female and 11 male with a mean age of 57.5 years. All 20 patients had uncontrolled type 2 diabetes with a mean diagnosis duration of 3.67 years. All patients had COVID-19-associated acute respiratory distress syndrome and received corticosteroids. The mean time interval between COVID-19 diagnosis and ROM diagnosis was 3.46 days. 4 patients (20%) had orbital apex syndrome, and 16 patients (80%) presented with orbital cellulitis. CT scan/MRI revealed sino-orbital involvement in all patients, and 3 of these had cerebral involvement at initial presentation. All 20 patients received intravenous amphotericin B and 7 patients received TRAMB and all 20 patients had undergone radical debridement of involved sinuses. Despite all measures, 3 (7.5%) of 20 patients with cerebral dissemination expired. Severe COVID-19 is associated with a significant incidence of ROM with higher mortality rates due to immune dysregulation and the widespread use of steroids. An aggressive multidisciplinary approach can help to reduce mortality.
Annapureddy Anusha, Samuel Cornelius Gnanadurai
Indian Journal of Clinical and Experimental Ophthalmology, Volume 8, pp 576-579; https://doi.org/10.18231/j.ijceo.2022.117

Abstract:
A 52-year-old male patient presented with a chief complaint of diminution of vision over the past two months. He is a known case of type -2 diabetes mellitus for 25 years but has not been taking his medication regularly. Ocular examination revealed visual acuity of 6/18 in both the eyes, xanthelasma, arcus senilis, posterior segment examination revealed creamy white discolouration of the retinal vessels. Routine blood investigation revealed high level of triglycerides (1550 mg/dl), cholesterol (615 mg/dl), LDL-C 10 mg/dl, HDL-C (187 mg/dl), and with HBA1C of 14.4%. Hence, diagnosed this case as lipaemia retinalis. The patient was referred to a physician for treatment, and after treating with statins, lipid-lowering therapy, and blood sugar control, the patient was reviewed every month; six months later, the patient had normal retinal vessels and improved visual acuity, in addition to normal triglyceride, cholesterol, and blood glucose levels.
Niaz Abdur-Rahman
Indian Journal of Clinical and Experimental Ophthalmology, Volume 8, pp 447-449; https://doi.org/10.18231/j.ijceo.2022.092

Abstract:
An overview on Anti-Vegf and in search for an ideal anti VEGF agent - IJCEO- Print ISSN No: - 2395-1443 Online ISSN No:- 2395-1451 Article DOI No:- 10.18231/j.ijceo.2022.092, Indian Journal of Clinical and Experimental Ophthalmology-Indian J Clin Exp Ophthalmol
Anjali Singh, Rajendra Prakash Maurya, Virendra Pratap Singh, Swati Gautam, Anil Kumar, C. P Mishra, P Jain, Shivangi Singh, Syeed Mehbub Ul Kadir, Farzad Pakdel, et al.
Indian Journal of Clinical and Experimental Ophthalmology, Volume 8, pp 458-467; https://doi.org/10.18231/j.ijceo.2022.094

Abstract:
To describe the epidemiology, patterns of ocular trauma, clinical presentation, visual outcome and prognostic factors of blunt ocular trauma.A teaching hospital based prospective observational study was conducted over a period of 4 years from March 2012 to Feb 2016. 226 patients of all age group fulfilling the various inclusion and exclusion criteria were included in the study. All patients underwent detailed protocol based workup including a comprehensive ocular examination along with relevant radiological tests. Data regarding demographic profile, etiology, circumstances of the injury, traumatic agents, mode and mechanism of injury, extent and severity of injury, clinical features, management and visual outcome was analyzed and prognostic factors including ocular trauma score were evaluated.Out of 402 total cases of ocular trauma, 226 caused by blunt objects were included in this study. 181 (80.1%) were male rest 45(19.9%) were female. The mean age was 42.6 ± 18.8 years. Blunt trauma was more prevalent in age group 16-25yrs (24.3%) followed by 26-35 years (23.9%). Majority (68.6%) of victims belonged to rural background. Most of the patients sustained trauma at road /street (30.5%) and home (27.9%). The most common cause of blunt trauma was road traffic accident (26.5%) followed by sports related injury (22.6%) and physical assault (21.7%). The most frequent traumatic agent was wooden object (26.0%) followed by stone / brick (25.2%) and metallic object (23.1%). Only 32.3% of patients had isolated ocular injuries, rest had associated polytrauma. 93.3% victims had unilateral ocular injury. Left eye (52.3%) was predominantly involved. Majority of injured eyes had more than 3 ocular structure involvement. Out of 241 injured eye 14.0% eyes had only globe injury while 61.4% eyes had simultaneous globe and adnexal injuries. 55.6% eyes had closed globe injury while 19.9% eyes had globe rupture. 20.7% eyes had purely posterior segment injury, while 23.2% eyes had both anterior and posterior segment injury. Most common clinical finding was corneal abrasion (45.6% eyes) followed by hyphema (44.0% eyes), traumatic mydriasis (35.7%), vitreous hemorrhage (33.2%) retinal detachment (20.3%), lens dislocation (22.8%) and traumatic cataract (17.4%). At the time of initial presentation 33.2% eyes had visual impairment and 35.7% eyes had blindness. 14.5% eyes with closed globe injury and 5.0% eyes with open globe injury had zone III injury. Ocular trauma score was in Category I in 14.9% injured eyes and in category II in 7.1% eyes. After 6 months 14.5% of the right eye and 24.2% of the left eye showed blinding outcome.Blunt trauma is the commonest mode of ocular injury. Young adult males are more vulnerable. Intraocular hemorrhage, zone III injury, posterior segment involvement and low ocular trauma score are poor prognostic factors.
, Shankar Narayan A
Indian Journal of Clinical and Experimental Ophthalmology, Volume 8, pp 439-441; https://doi.org/10.18231/j.ijceo.2022.089

Abstract:
Oculomyiasis: An overview - IJCEO- Print ISSN No: - 2395-1443 Online ISSN No:- 2395-1451 Article DOI No:- 10.18231/j.ijceo.2022.089, Indian Journal of Clinical and Experimental Ophthalmology-Indian J Clin Exp Ophthalmol
Nanthene Rajmohan, Venipriya, Hannah Ranjee Prasanth, Ravichandran Kandasamy
Indian Journal of Clinical and Experimental Ophthalmology, Volume 8, pp 492-495; https://doi.org/10.18231/j.ijceo.2022.099

Abstract:
Pseudoexfoliation (PXF) syndrome is an age-related process of unknown etiology characterized by the deposition of distinctive fibrillar material in the anterior segment of the eye. The material is commonly deposited in the anterior chamber, angle of the eye, iris, trabecular meshwork, anterior capsule of the lens, and also the cornea. It is associated with open and narrow angle glaucoma, the formation of cataracts and the corneal endothelial decompensation.PXF deposition in the lens zonules leads to disintegration of the lens zonules resulting in lens subluxation and dislocation. PXF deposition on the iris causes poor pupillary dilatation. Both zonular dehiscence and poor pupillary dilatation pose a great challenge to the cataract surgeon during surgery. Intra operatively, the chances of lens subluxation / dislocation, posterior capsular rupture, vitreous loss is high in the presence of pseudoexfoliation. In the immediate post-operative period, intra ocular pressure spikes, increased and prolonged iritis and corneal decompensation can affect the visual outcome of the surgery. This study will retrospectively analyze the clinical profile of the patients with pseudoexfoliation and to evaluate the occurrence of intra and immediate post-op complications of cataract surgery. In this way, the surgeon can plan his/her surgical technique to help avoid complications during cataract surgery and be prepared to manage the potential intraoperative and postoperative complications that can occur in pseudoexfoliation eyes.
Aliya Sultana, Varsha Mallapragada
Indian Journal of Clinical and Experimental Ophthalmology, Volume 8, pp 543-548; https://doi.org/10.18231/j.ijceo.2022.110

Abstract:
: Purpose is to study the various typical and atypical manifestations of the retinoblastoma presented to our department.: Prospective study.: 2 years, January 2020 to December 2021.: All children presented with various signs and symptoms and cases with tumour suspicious manifestations were evaluated. Detailed birth history from parents, slit lamp examination, indirect ophthalmoscopy, B Scan, CT Scan Orbit (plain and contrast), MRI Orbit (plain and contrast) when tumour extension was suspected and documentation done in all cases.: Atypical manifestations requires proper evaluation to exclude Pseudo retinoblastomas. Many clinical conditions will masquerade the tumour and cause confusion in diagnosis. Pseudo retinoblastomas which reported in our study were commonly PHPV and Coats disease. One case of Retinoblastoma was also presented like Ocular cysticercosis with inflammatory signs in anterior and posterior segment, oral steroids were given, vitreous seeds which were present in anterior chamber disappeared after steroids and fundus showed creamish white lesion filling the entire vitreous cavity. Masquerades will cause delay in the diagnosis, which can lead to extension of tumour.: Diagnosis is not easy, most of the times in children particularly when media is not clear, delay in diagnosis may require enucleation where globe salvage may not be possible, sometimes intracranial extension of the tumour will increase the mortality.
Naziya Md Rizwan Shaikh, Aditi Dubey, Kavita Kumar, G Aishwarya, Surendra Singh Kansana
Indian Journal of Clinical and Experimental Ophthalmology, Volume 8, pp 509-513; https://doi.org/10.18231/j.ijceo.2022.103

Abstract:
The aim of this study was to identify the factors influencing the duration of spontaneous regression of Retinopathy of Prematurity. A prospective observational study was conducted over a duration of 1.5 years from December, 2019 to May, 2021. All the infants presenting with ROP or developed any stage later were considered for the study and were followed up as per International Classification of Retinopathy Guidelines (ICROP), 2005 guidelines till compete vascularisation. Data regarding the birth history and maternal factors were noted. In those neonates in whom the Retinopathy of Prematurity presented or progressed to type 1 ROP were treated and the rest were followed up till complete vascularisation and duration noted. Risk factors were compared in neonates undergoing spontaneous regression within 45 weeks PMA and those taking longer than 45 weeks. The Statistical analysis was performed by SPSS 23.0 version. Mean gestational age in neonates undergoing earlier spontaneous regression (<45 weeks) was 31.86±2.02 months, and that of delayed spontaneous regression group was 33±2.24 months. Mean birth weight in earlier spontaneous regression group was 1537.14±202.02 grams, and that delayed spontaneous regression group was 1406.19±229.88 grams. Mean duration of complete regression of ROP is 44.9 weeks postmenstrual age. Higher birth weight and Hyperbilirubinemia was found to significantly cause the regression of ROP within 45 weeks (P=0.021). Higher birth weight and Hyperbilirubinemia was found to cause earlier regression of ROP and hence could be a possible protective factor in the pathogenesis of ROP.
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